Computational and structural studies of gene silencing mechanisms

基因沉默机制的计算和结构研究

• 批准号: 172674
• 负责人: Major François
• 金额: $ 42.03万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=172674&lang=en
• 关键词: Computational Modeling; Gene Expression Mechanisms And Pathways; Nmr; Physicochemical Properties; Structural And Genomic Data; X-Ray Crystallography

Nature has developed mechanisms to protect living organisms against external intruders such as viruses, or internal dysfunction such as cancer. One such security mechanism is shutting down genes, also known as gene silencing. Gene silencing is at the hear

大自然已经发展出保护生物体免受外部入侵者（如病毒）或内部功能障碍（如癌症）的机制。其中一种安全机制是关闭基因，也称为基因沉默。基因沉默是在听