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Mechanisms sustaining abnormal peripheral sensory signaling in the abdomen in a model of post-infectious IBS: A dynamic interplay of peripheral and central factors.

Mechanisms sustaining abnormal peripheral sensory signaling in the abdomen in a model of post-infectious IBS: A dynamic interplay of peripheral and central factors.
感染后IBS模型中腹部异常外周感觉信号的维持机制：外周和中枢因素的动态相互作用。
批准号：
209648
负责人：
Vanner Stephen J
金额：
$54.03万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-09-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=209648&lang=en
关键词：
Abdominal Pain Diarrhea Dorsal Root Ganglia Neurons Electrophysiology Infectious Colitis Irritable Bowel Syndrome

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Irritable bowel syndrome (IBS) is a very common disorder for which there are currently no proven treatments. This proposal examines causes of pain in patients suffering from post-infectious IBS (IBS which onsets following an acute bacterial infection in t
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