Research Initiation Award: Design of Auxiliary Chromosomes for Escherichia coli
Research Initiation Award: Design of Auxiliary Chromosomes for Escherichia coli
批准号:
9409603
负责人:
Jay Keasling
金额:
$11.8万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-07-15 至 1997-06-30
中文摘要
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英文摘要
9409603 Keasling The goals of this project are to understand how low-copy plasmids are maintained in bacteria by quantifying the cell-cycle replication patterns, the degree of segregative stabilization, and the metabolic burden of naturally-occurring replication and segregation elements. This information is to be used to design and engineer chromosome-like vehicles in applications involving complex cellular manipulations and requiring a high degree of regulation. Escherichia coli is to be used as the subject for these investigations, because metabolism and macromolecular synthesis are well understood in this organism. ***
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批准号:1565318
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依托单位:
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批准号:1437775
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资助金额:$37.71万
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财政年份:2014
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负责人:Jay Keasling
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批准号:1442724
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依托单位:
Synthetic Biology of Yeast
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批准号:1330914
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资助金额:$517.41万
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财政年份:2013
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依托单位:
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依托单位:
ARS Synthetica - A Multimedia Forum Exploring the Artful Design of Living Things
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批准号:0853031
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财政年份:2009
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依托单位:
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ME: Metabolic Engineering of Isoprenoid Production
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批准号:9911463
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资助金额:$22.62万
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依托单位:
Engineering mRNA Stability for Coordinated Expression of Multiple Genes in New Operons
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批准号:9906405
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财政年份:2000
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负责人:Jay Keasling
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依托单位:
ME: Strategies for Metabolic Engineering of Environmental Microorganisms - Applications to Degradation of Organophosphate Contaminants
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批准号:9814088
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项目类别:Continuing Grant
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财政年份:1998
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负责人:Jay Keasling
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依托单位:
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批准号:9502495
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依托单位:
海外基金