Research Initiation Award: Anaerobic Biotransformation of Environmental Pollutants by Microbial Co-Enzymes

这是为一个项目提供支持的奖项，该项目的总体目标是研究氯化有机化合物的还原性脱氯和微生物辅酶介导的金属生物甲基化的相互作用。研究人员计划在三个重叠的阶段进行这项研究，其中最初的一个阶段将描述实验条件，在这种条件下，汞等金属在特定的化学系统中发生甲基化。然后，他计划在类似的化学条件下检测金属甲基化与还原性脱氯结合的情况，然后确定这些过程在厌氧沉积物中单独发生和联合发生的速率。空气、水、土壤、沉积物和含有污染物混合物的污泥的净化，每一种污染物都需要不同的去除或转化程序，这在旨在恢复受污染介质的有用品质的过程和系统的工程设计中提出了一个特殊问题。研究结果将为重金属和氯化有机化合物混合物污染的环境介质净化过程的工程设计提供指导。该提案是根据NSF 92-122“研究启动奖励计划”提交的。* * *

9410363 Nies This is an award to provide support for a project, the overall objective of which is to study interactions of reductive dechlorination of chlorinated organic compounds and the biomethylation of metals mediated by microbial coenzymes. The investigator plans on doing this in three overlapping periods, the initial one of which will characterize the experimental conditions under which methylation of metals like mercury occurs in a defined chemical system. He then plans on examining the methylation of metals when combined with reductive dechlorination under similarly defined chemical conditions followed by determination of the rates at which these processes occur individually and combined in anaerobic sediments. The decontamination of air, water, soil, sediments and sludges containing mixtures of pollutants, each of which requires a different removal or transformation procedure, poses a special problem in the engineering design of processes and systems that are aimed at restoration of the useful qualities of the contaminated media. Results will provide guidance for engineering design of processes to decontaminate environmental media contaminated by mixtures of heavy metals and chlorinated organic compounds. The proposal leading to this award was submitted in accord with NSF 92-122, Research Initiation Awards Program. ***