Testing co-evolutionary processes driving venom diversity in tiger snakes

测试驱动虎蛇毒液多样性的共同进化过程

• 批准号: LP160100189
• 负责人: Dr Vicki Thomson
• 金额: $ 11.39万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-12 至 2021-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP160100189
• 关键词: Testing; co; evolutionary; processes; driving

Testing co-evolutionary processes driving venom diversity in tiger snakes. This project aims to examine the geographic variation amongst tiger snakes in anatomy, ecology, and life history traits, and the relationship of these factors to venom toxins and production; and to evaluate the true pharmacological potential of tiger snake venom. This project will investigate the role of venom adaptation in long-term animal evolution, by identifying rare venom transcripts involved in providing evolutionary potential for adaptation to environmental change. This is essential as continuing climatic and human-induced alteration of our environment affects southern Australia where many people live, work and interact with native wildlife. Anticipated outcomes are maximizing venom harvests and enhanced snakebite treatment capacity.

测试驱动虎蛇毒液多样性的共同进化过程。本项目旨在研究虎蛇在解剖学、生态学和生活史特征上的地理差异，以及这些因素与毒液毒素和生产的关系；并评估虎蛇毒的真正药理潜力。该项目将研究毒液适应在长期动物进化中的作用，通过识别罕见的毒液转录物，为适应环境变化提供进化潜力。这是至关重要的，因为持续的气候和人为引起的环境变化影响着澳大利亚南部，许多人在那里生活、工作，并与当地野生动物互动。预期的结果是最大限度地获得毒液和增强蛇咬伤治疗能力。