Countdown to death: defining new signalling events preceding cell death

死亡倒计时：定义细胞死亡前的新信号事件

• 批准号: FT220100742
• 负责人: Dr Najoua Lalaoui
• 金额: --
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-07-01 至 2022-07-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT220100742
• 关键词: Countdown; death; defining; new; signalling

This proposal aims to understand how programmed cell death molecular machineries promote innate immune responses and proliferation by identifying new molecules that regulate these fundamental biological processes. This project expects to enhance our basic understanding of cell death, cell proliferation and innate immunity using innovative approaches and to build interdisciplinary collaborations. The new generated knowledge in these critical processes will be fertile ground to develop innovative applications in biomedical industries. This this will have a positive impact on the health and economy of Australian society.

该建议旨在了解编程的细胞死亡分子机器如何通过鉴定调节这些基本生物学过程的新分子来促进先天免疫反应和增殖。该项目希望通过创新方法增强我们对细胞死亡，细胞增殖和先天免疫的基本理解，并建立跨学科的合作。在这些关键过程中，新产生的知识将是肥沃的基础，以在生物医学行业开发创新的应用。这将对澳大利亚社会的健康和经济产生积极影响。