Functional Protein Dynamics in Health and Disease

健康和疾病中的功能蛋白动态

• 批准号: 354060
• 负责人: Kay Lewis E
• 金额: $ 360.79万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-10-01 至 2023-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=354060&lang=en
• 关键词: Nmr Spectroscopy; Nucleosome Protein Interactions; P97; Proteasome; Protein Aggregation; Protein Conformational States; Protein Dynamics; Protein Energy Landscape; Protein Thermodynamics; Superoxide Dismutase

Protein molecules play critical roles in cellular function and they catalyze many of the biochemical reactions that are necessary for life. The three-dimensional shapes of these molecules are necessary for guiding proper function and they can change with

蛋白质分子在细胞功能中起着关键作用，它们催化生命所必需的许多生化反应。这些分子的三维形状对于引导适当的功能是必要的，并且它们可以随着时间的推移而改变。