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Exploring the evolutionary battle between phages and bacteria: from CRISPR-Cas systems to phage-derived antibacterial weapons

Exploring the evolutionary battle between phages and bacteria: from CRISPR-Cas systems to phage-derived antibacterial weapons
探索噬菌体和细菌之间的进化之战:从 CRISPR-Cas 系统到噬菌体衍生的抗菌武器
批准号:
355205
负责人:
Davidson Alan R
金额:
$301.74万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2023-10-01

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中文摘要
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英文摘要
My work focuses on viruses that infect bacteria, called phages. Bacteria have developed "immune" systems to protect themselves from attack by phages. One of these systems is known as CRISPR-Cas and it is able to cleave phage genomes at specific spots, gui
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Investigating the battle between CRISPR-Cas systems and anti-CRISPRs using biochemical, genetic, and evolutionary approaches
  • 批准号:
    480052
  • 项目类别:
    Operating Grants
  • 资助金额:
    $82.76万
  • 财政年份:
    2023
  • 负责人:
    Davidson Alan R
  • 依托单位:
Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384866
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Davidson Alan R
  • 依托单位:
Developing phage tail-derived nanomachines as strain specific antibacterial agents
  • 批准号:
    358137
  • 项目类别:
    Operating Grants
  • 资助金额:
    $68.83万
  • 财政年份:
    2016
  • 负责人:
    Davidson Alan R
  • 依托单位:
Characterization of Newly Discovered Proteins that Inhibit the CRISPR/Cas Adaptive Immunity Systems of Bacteria
  • 批准号:
    282206
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.02万
  • 财政年份:
    2013
  • 负责人:
    Davidson Alan R
  • 依托单位:
海外基金