Regulating the dynamic cycling of palmitate on proteins

调节棕榈酸酯对蛋白质的动态循环

• 批准号: 390032
• 负责人: Conibear Elizabeth
• 金额: $ 54.34万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=390032&lang=en
• 关键词: Alpha/Beta Hydrolase; Nras; Palmitoylation; Protein Localization; Protein Modification; S-Acylation; Signaling

Proteins are essential for all processes in our cells. Some proteins can be modified by the repeated addition and removal of a fatty molecule called palmitate. This process, termed the "palmitoylation cycle", helps direct these proteins to parts of the ce

蛋白质对我们细胞中的所有过程都是必不可少的。一些蛋白质可以通过反复添加和去除一种叫做棕榈酸酯的脂肪分子来修饰。这一过程被称为“棕榈酰化循环”，有助于将这些蛋白质引导到细胞的某些部位。