Assembly of Low-Cost FTNMR Spectrometer for Undergraduate Instruction

9451570 Jameson这个建议是从一台退役的光谱仪组装一台200兆赫的核磁共振光谱仪，用于本科教学。我们建议只利用低电平射频部分和旧系统的磁铁。转换包括一个最先进的基于PC的计算机、外设、定时部分和脉冲编程器。结果将是一个将在许多本科课程中常规使用的高场光谱仪。在洛约拉大学，我们将改变我们的教学方法，从一开始在有机课程中几乎不存在实际操作的核磁共振波谱，转变为一种高场光谱仪在课程中扮演常规和不可分割的一部分，将采集与处理分开，从而使25名学生在一个小时的实验室中获得光谱。在仪器分析中，学生将了解时域和频域数据之间的转换。他们将深入了解实验参数的最佳控制与仪器设计相关的方式。我们希望我们的本科生能够更加熟练地使用核磁共振波谱，从而使他们的本科研究得到极大的丰富，并为他们未来的化学事业做好更好的准备。我们建议，从现有的商业模块组装一个核磁共振光谱仪用于本科教学是完全可能的，在有能力的光谱学家（核磁共振与否）或仪器分析讲师的能力范围内。我们将证明，光谱仪可以获得成本远低于10万美元。10年（完全可维修）的4.7T磁铁（200mhz 1H）正在从旧仪器退役中获得，价格（15-35K美元）取决于可用性，额外费用和需求。一个非常有用的教学工具是可能的。

9451570 Jameson This proposal is for the assembly of a 200 MHz NMR spectrometer for undergraduate instruction from a decommissioned spectrometer. We propose to utilize only the low-level rf section and the magnet from older systems. The transformation includes a state of the art PC based computer, peripherals, timing section, and pulse programmer. The result will be a high-field spectrometer which will be routinely used in many undergraduate courses. At Loyola University we will transform our pedagogy from one in which hands-on NMR spectroscopy is almost non-existent in the beginning Organic courses into one in which a high-field spectrometer plays a routine and integral part of the course, separating acquisition from processing, thereby making possible 25 student spectra in one hour of laboratory. In Instrumental Analysis the students will understand the conversion between time and frequency domain data. They will delve into understanding the manner in which optimal control of experimental parameters is related to instrument design. We wish to have our undergraduate students become more sophisticated in the use of NMR spectroscopy so that their undergraduate research will be significantly enriched, and make them better prepared for their future chemistry careers. We suggest that assembling an NMR spectrometer for undergraduate instruction from existing commercial modules is quite possible, well within the competence of capable spectroscopists (NMR or not) or Instrumental Analysis instructor. We will demonstrate that a spectrometer can be obtained for a cost well below $100,000. Ten year old (entirely serviceable) 4.7T magnets (200 Mhz 1H) are becoming available from the decommissioning of older instruments, prices ($15-35K) depending on availability, extras and demand. An extremely useful instructional tool is possible.