Mechanisms of particle destruction and cytokine induction during phagocytosis in macrophages

巨噬细胞吞噬过程中颗粒破坏和细胞因子诱导的机制

• 批准号: 401674
• 负责人: Harrison Rene E
• 金额: $ 55.45万
• 依托单位: University of Toronto Scarborough (ON)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=401674&lang=en
• 关键词: Cytokines; Inflammation; Macrophages; Opsonin; Phagocytosis; Phagosome

Macrophages are cells that are part of the innate immune system. These cells are specialized to perform a process called phagocytosis, whereby dying cells are engulfed and digested by the macrophage. Macrophages also clear the body of pathogens by binding

巨噬细胞是先天免疫系统的一部分。这些细胞被专门用来完成一个叫做吞噬作用的过程，在这个过程中，垂死的细胞被巨噬细胞吞噬和消化。巨噬细胞还可以通过结合清除体内的病原体