An FT NMR System for Undergraduate Instruction

9452527摩尔200兆赫兹傅立叶变换核磁共振谱仪/系统正在我们的基础有机化学本科实验室中使用，我们在那里教授大量的理工科学生。与此同时，学生(主要是专业)在更高级的实验室课程中大量使用这种仪器，这些课程包括结构阐明、有机和无机合成、物理化学和本科生研究。有一种仪器可以满足这些课程学生的不同需求，因为现代FT核磁共振光谱仪非常灵活。可以对它们进行编程，以允许快速周转以获得许多“常规”光谱，同时保留更高级工作所需的所有实验所需的所有潜力。在基础(“二年级”)有机实验室，我们能够让学生有机会将核磁共振应用于他们自己的实验室工作，这越来越多地涉及到一种“调查”的方法。在一台仪器上处理大量学生的后勤工作并不是微不足道的。在高级课程中，我们处理较小的数字，学生有足够的仪器时间，包括“休息时间”，不仅获得高分辨率的光谱，而且还做许多其他复杂的实验，包括双共振去耦合，L3C-OFF共振，NOE，2D-核磁共振，变温和弛豫现象等。此外，我们为学生提供我们自己的谱库，记录在“他们的”仪器上，用于授课和相关研究。该仪器通过让学生接触到现代FT核磁共振系统，对许多学生的教育产生了重大影响--每年数百人。

9452527 Moore A 200 MHz FT NMR spectrometer/system is being used in our undergraduate laboratories in basic organic chemistry, where we teach large numbers of science and engineering students. At the same time, this instrument is being heavily utilized by students (mostly majors) in more advanced laboratory courses in structure elucidation, organic and inorganic synthesis, physical chemistry and undergraduate research. One instrument is meeting the differing needs of students in these courses because modern FT NMR spectrometers are so flexible. They can be programmed to permit the fast turnover needed to obtain many "routine" spectra while retaining all of the potential needed for the full range of experiments needed in more advanced work. In the basic ("sophomore") organic laboratory, we are able to give students the opportunity to apply NMR to their own laboratory work, which increasingly involves an "investigative" approach. The logistics of handling large numbers of students on one instrument are not trivial. In the advanced courses, where we deal with smaller numbers, students have adequate instrument time, including "off-hours", not only to obtain high-resolution spectra, but also to do many other sophisticated experiments, including double resonance decoupling, l3C-off resonance, NOE, 2D-NMR, variable temperature and relaxation phenomena, etc. In addition, we provide students with our own library of spectra, recorded on "their" instrument, to be used in lectures and associated study. This instrument is having a major impact on the education of many students - several hundred per year - by giving them access to a modern FT NMR system.