Ciliary Pathways in Neurogenetic Disease

神经遗传疾病中的纤毛通路

• 批准号: 402180
• 负责人: Lehmann Ordan J
• 金额: $ 61.86万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=402180&lang=en
• 关键词: Ciliopathy; Glaucoma And Hydrocephalus; Hedgehog Signaling; Model Organism (Zebrafish); Transcription Factor Mutation

Cilia function a bit like a satellite antenna, protruding from most cells and relaying information from the surroundings back to the cell. An increasing number of conditions are being identified where cilia function abnormally, and these disorders (termed

纤毛的功能有点像卫星天线，从大多数细胞中伸出，将周围环境的信息传递回细胞。越来越多的条件正在确定纤毛功能异常，这些疾病（称为