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For Improving diagnostics and grasping the disease mechanisms of rare hypomagnesemia in patients with CNNM2 mutations

For Improving diagnostics and grasping the disease mechanisms of rare hypomagnesemia in patients with CNNM2 mutations
改善 CNNM2 突变患者罕见低镁血症的诊断并掌握其疾病机制
批准号:
406731
负责人:
Tremblay Michel L
金额:
$16.39万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-06-01 至 2022-06-01

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中文摘要
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英文摘要
Low blood magnesium (hypomagnesemia) is a common electrolyte disorder that causes fatigue, muscle cramps, and arrhythmias. The CNNM2 gene encodes a protein that is responsible for the transport of magnesium in the kidney, the primary organ responsible for
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Molecular and physiological understanding of the protein tyrosine phosphatome towards clinical applications.
  • 批准号:
    369211
  • 项目类别:
    Operating Grants
  • 资助金额:
    $219.29万
  • 财政年份:
    2017
  • 负责人:
    Tremblay Michel L
  • 依托单位:
Improving macrophage innate immunity by modulating protein tyrosine phosphatases: the complete mouse and human PTPomes
  • 批准号:
    346783
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2016
  • 负责人:
    Tremblay Michel L
  • 依托单位:
Generation of a new therapeutic approach against advanced pancreatic cancer by modulating protein tyrosine phosphatases
  • 批准号:
    341726
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.28万
  • 财政年份:
    2016
  • 负责人:
    Tremblay Michel L
  • 依托单位:
New understanding and targets from the human phosphatome: towards the treatment of castration-resistant prostate cancer.
  • 批准号:
    366581
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Tremblay Michel L
  • 依托单位:
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