Development of Small Macrocyclic Antibody-Like Scaffolds (SMALS) for therapeutic inhibition of Nodal
开发用于治疗性抑制 Nodal 的小大环抗体样支架 (SMALS)
基本信息
- 批准号:408349
- 负责人:
- 金额:$ 61.3万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2019
- 资助国家:加拿大
- 起止时间:2019-09-01 至 2024-09-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
NODAL is a protein that is normally in stem cells but that re-emerges in cancer, where it promotes cancer progression and metastasis. We have recently shown that NODAL may drive chemoresistance in ovarian cancer. Accordingly, inhibiting NODAL seems to imp
NODAL是一种通常存在于干细胞中的蛋白质,但它会在癌症中重新出现,促进癌症的进展和转移。我们最近发现NODAL可能导致卵巢癌的化疗耐药。因此,抑制NODAL似乎很重要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Derda Ratmir其他文献
Derda Ratmir的其他文献
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{{ truncateString('Derda Ratmir', 18)}}的其他基金
Probing the Role of Glycans in Immunooncology using Genetically Encoded "Liquid Glycan Arrays"
使用基因编码的“液体聚糖阵列”探讨聚糖在免疫肿瘤学中的作用
- 批准号:
453419 - 财政年份:2021
- 资助金额:
$ 61.3万 - 项目类别:
Operating Grants
Chemical genetic screen for cell surface receptors that control cancer stem cell differentiation
控制癌症干细胞分化的细胞表面受体的化学遗传筛选
- 批准号:
313957 - 财政年份:2014
- 资助金额:
$ 61.3万 - 项目类别:
Operating Grants
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