Development of Small Macrocyclic Antibody-Like Scaffolds (SMALS) for therapeutic inhibition of Nodal
Development of Small Macrocyclic Antibody-Like Scaffolds (SMALS) for therapeutic inhibition of Nodal
批准号:
408349
负责人:
Derda Ratmir
金额:
$61.3万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01
中文摘要
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英文摘要
NODAL is a protein that is normally in stem cells but that re-emerges in cancer, where it promotes cancer progression and metastasis. We have recently shown that NODAL may drive chemoresistance in ovarian cancer. Accordingly, inhibiting NODAL seems to imp
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批准号:453419
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项目类别:Operating Grants
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资助金额:$68.83万
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财政年份:2021
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负责人:Derda Ratmir
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依托单位:
Chemical genetic screen for cell surface receptors that control cancer stem cell differentiation
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批准号:313957
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2014
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负责人:Derda Ratmir
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依托单位:
海外基金