Functional roles of glycogen synthase kinase-3 in cellular regulation and cancer

糖原合成酶激酶 3 在细胞调节和癌症中的功能作用

• 批准号: 189383
• 负责人: Woodgett James (Jim) R
• 金额: $ 73.14万
• 依托单位: Lunenfeld-Tanenbaum Research Institute (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=189383&lang=en
• 关键词: Beta-Catenin; Colon Cancer; Development; Lymphoma; Protein Kinase; Stem Cell

We have been studying a pair of proteins that have an unusual function as gate-keepers in tissues by providing a throttle to signals that normally promote growth and adoption of particular cell fates. The growth inhibitory effects of these proteins is cle

我们一直在研究一对蛋白质，它们在组织中具有不同寻常的把关功能，通过对通常促进生长和采用特定细胞命运的信号提供节流。这些蛋白质的生长抑制作用是明显的。