Development of Conducting Polymer Ion Selective Microelectrodes for Use in Environmental and Biomedical Analyses, US-Egypt Cooperative Research

产品描述：该项目支持辛辛那提大学土木与环境工程系的Paul Bishop博士和化学系的Harry Mark博士与Ahmed G. Abdo，开罗大学理学院化学系。 所提出的工作的目标将是导电聚合物作为阴离子和生物分子传感器在3电极设置和流动系统中的分析应用，以及离子选择性电极和预浓缩装置。 这些应用的典型例子是用于水质和污染控制的阴离子测定以及生物医学和工业利益的一些生物分子的测定。 将使用通过化学和电化学合成制备的导电聚合物和官能化聚合物。 希望在阴离子，阳离子和分子分析领域开发新的分析技术，其中水性环境和生物医学样品需要新的检测器，这是美国和埃及的主要关注点。 导电聚合物微电极也将被设计用于人体体液中的有效体内分析和细胞间或细胞内检查。 后一种应用尚未得到广泛开发，预计将作出富有成效的努力。 适用范围：该项目将允许Mark博士在电化学和有机聚合物方面的专业知识之间的合作活动; Bishop博士的专业知识是有毒有机物的生物降解和生物膜中的运输，以及Abdo博士最近获得博士学位。(from联合辛辛那提），在聚合物和化学传感器的分析应用，以及电化学的专业知识。该项目包括阿卜杜博士对辛辛那提进行为期两个月的访问，以及一名美国参与者在三年内每年对开罗进行一次访问。 这项研究的结果可能会有一些深远的应用，并可能为两国带来经济和环境效益。 该项目符合国际项目司的目标，即在专业知识和能力互补的情况下，将美国科学家与外国科学家联系起来，并且该项目可以导致长期合作和互利的结果。

Description: This project supports cooperation between Drs. Paul Bishop, Department of Civil and Environmental Engineering, and Harry Mark, Department of Chemistry, at the University of Cincinnati, and Dr. Ahmed G. Abdo, Department of Chemistry, Faculty of Science, University of Cairo. The target of the proposed work will be the analytical applications of conducting polymers as anion and biological molecule sensors in a 3-electrode set-up and in flow systems, as well as ion selective electrodes and preconcentration devices. Typical examples of these applications are in the fields of anion determination for water quality and pollution control and the determination of some biological molecules of biomedical and industrial interest. Conducting polymers and functionalized polymers prepared by chemical and electrochemical synthesis will be used. It is hoped to develop novel analytical techniques in the fields of anion, cation and molecular analyses where novel detectors are needed for aqueous environmental and biomedical samples, which are of primary concern in the U.S. and in Egypt. Conducting polymer micro-electrodes will also be designed for effective in vivo analysis in human body fluids and inter- or intra-cellular examinations. The latter application has not been extensively exploited and productive efforts are anticipated. Scope: This project will allow a cooperative activity between Dr. Mark who has expertise in electrochemistry and organic polymers; Dr. Bishop whose expertise is in biodegradation of toxic organics and transport in biofilms, and Dr. Abdo who is a recent Ph.D. (from U. Cincinnati) with expertise in analytical applications of polymers and chemical sensors, as well as electrochemistry. The project involves a visit by Dr. Abdo to Cincinnati for two months, and one visit by a US participant to Cairo in each of three years. The results of the research could have some profound applications, and could lead to economic and environmental benefits, for both countries. The project meets the objectives of the Division of International Programs in linking US scientists with foreign scientists when the expertise and capabilities are complementary, and where the project could lead to long term collaboration and to mutually beneficial results.