Blue-Light Signal Transduction in Chlamydomonas Reinhardtii

MCB 9509028盖尔事项 该项目将启动蓝光对植物基因表达调控的研究，并开始鉴定蓝光信号转导中间体。 该实验系统是基于编码谷氨酸-1-半醛氨基转移酶的基因，该酶在叶绿素生物合成途径的早期起作用。 该项目将确定参与蓝光调控基因表达的启动子区域，并可能导致对与这些DNA序列相互作用的因子的进一步研究。 此外，该项目还将研究潜在的蓝光信号化合物，包括cAMP，cGMP，钙和钙调素，这些化合物参与高等植物的信号传导。 这个项目将确定细胞内的成分相互作用的机制，以响应刺激，如暴露于光。 ***

MCB 9509028 Gail Matters The project will initiate a study of blue-light regulation of plant gene expression and begin to identify blue-light signal transduction intermediates. The experimental system is based on the gene encoding glutamate-1-semialdehyde aminotransferase, an enzyme which acts early in the chlorophyll biosynthetic pathway. The project will identify promoter regions involved in blue light regulated gene expression and may lead to further studies on a factor(s) which interacts with these DNA sequences. In addition, the project will examine potential blue light signaling compounds including cAMP, cGMP, calcium, and calmodulin which are involved in signaling in higher plants. %%% This project will identify mechanisms by which components within cells interact in response to a stimulus such as exposure to light. ***