Epigenetic signatures in sepsis-survivors associated with one-year outcome: A model-based clustering analysis of prospective cohorts

脓毒症幸存者的表观遗传特征与一年的结果相关：基于模型的前瞻性队列聚类分析

• 批准号: 457220
• 负责人: Soussi Sabri M
• 金额: $ 7.65万
• 依托单位: St. Michael's Hospital (Toronto, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-10-01 至 2024-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=457220&lang=en
• 关键词: Biomarkers; Circulating Micrornas; Clustering; Critical Care Medicine; Epigenetics; Long-Term Outcomes; Sepsis-Survivors; Translational Medicine

In Canada, sepsis strikes young and old alike with an incidence of ~100 000 cases per year. Mortality remains between 20 and 40%, and the incidence is rising (8.7%/year). Survivors have long term morbidity and elevated risk of death. The risk of having po

在加拿大，败血症袭击年轻人和老年人，每年约有100 000例。死亡率保持在20%至40%之间，发病率正在上升（8.7%/年）。存活者有长期发病和死亡风险升高。有风险的PO