Functions of a Conserved Herpesvirus Tegument Protein

保守的疱疹病毒外皮蛋白的功能

• 批准号: 468498
• 负责人: Banfield Bruce W
• 金额: $ 62.42万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468498&lang=en
• 关键词: Capsid Envelopment; Early Events In Virus Infection; Herpesvirus Infection; Mitochondrial Function; Molecular And Cellular Biology; Tegument Proteins; Ul16; Virus Assembly

We study the herpes simplex viruses HSV-1 and HSV-2, which infect ~3.7 billion and ~500 million people, respectively. These viruses cause lifelong infections for which there is no cure. Resistance to existing HSV drugs is a problem, particularly in people

我们研究单纯疱疹病毒HSV-1和HSV-2，它们分别感染约37亿和约5亿人。这些病毒导致终身感染，目前尚无治愈方法。对现有HSV药物的耐药性是一个问题，特别是在人