RUI: Arabidopsis Type 2A Protein Phosphatase Regulatory Subunit B

RUI：拟南芥 2A 型蛋白磷酸酶调节亚基 B

• 批准号: 9603782
• 负责人: Sabine Rundle
• 金额: $ 25.51万
• 依托单位: Western Carolina University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9603782&HistoricalAwards=false
• 关键词: RUI; Arabidopsis; Type; 2A; Protein

9603782 Rundle The work will investigate protein phosphatase 2A isoforms in Arabidopsis thaliana. This family of phosphatases is involved in a number of developmental processes in plants and in the sensing and signal transduction of environmental cues. Not much work has been focused on these proteins in plants - major emphasis has up to now been given to the corresponding protein kinases. The work will utilize conserved regions to amplify the phosphatases, will study the genomic organization of family members, characterize transcripts, examine their cellular localization, and work towards a protein expression and analysis system. These are long-range goals for this young investigator. More short term objectives include the training of undergraduate students and setting up the experimental system. The PP2A family is receiving more attention at the moment in plants because of the pivotal role of the proteins in plant environment interactions, making such work timely and worthy of systematic investigations.

9603782 Rundle这项工作将研究拟南芥中的蛋白磷酸酶2A亚型。 该磷酸酶家族参与植物的许多发育过程以及环境信号的感知和信号转导。 植物中的这些蛋白质没有太多的研究，到目前为止，主要的重点是相应的蛋白激酶。 这项工作将利用保守区域来扩增磷酸酶，将研究家族成员的基因组组织，表征转录本，检查它们的细胞定位，并致力于蛋白质表达和分析系统。 这些都是这位年轻研究员的长期目标。 近期目标包括培养本科生和建立实验体系。 PP2A家族由于在植物与环境相互作用中的关键作用而在植物中受到更多的关注，使得此类工作及时且值得系统研究。