Acquisition of Departmental Mass Spectrometers

9632905 Hackert University of Texas Austin化学研究仪器和设施（CRIF）计划和学术研究基础设施（ARI）计划的这一奖项将帮助德克萨斯大学奥斯汀分校的化学生物化学系获得质谱仪。这些设备将加强若干领域的研究，包括：（1）在不寻常环境中的光诱导电子转移（2）RNA结构和RNA-蛋白质相互作用的结构基础（3）π-束的分子量和结构信息，具有非共价高级结构的合成大分子（4）分子量为几千Da的扩展卟啉和抗病毒剂合成载体的质量测量。（5）小分子之间氢键驱动的分子识别，和（6）新生肽。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超过任何其他技术。电喷雾电离与高分辨率结合使用提供了质谱分析中可用的最新技术。它为化学家提供了表征化合物的最强大的工具之一。在质谱分析中获得这种能力对于许多化学领域的前沿研究至关重要。

9632905 Hackert University of Texas Austin This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Academic Research Infrastructure (ARI) Program will assist the Department of Chemistry & Biochemistry at the University of Texas Austin acquire a Mass Spectrometer. This equipment will enhance research in a number of areas including the following: (1) photo induced electron transfer in unusual environments (2) RNA structure and the structural basis of RNA-protein interactions (3) molecular weight and structural information of pi-beams, large synthetic molcules with noncovalent higher order structures (4) mass measurements of expanded porphyrins and synthetic carriers for antiviral agents with molecular weights of several thousand Da. (5) hydrogen-bond-driven molecular recognition between small molecules, and (6) nascent peptides. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic,bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.