Modeling and Computational Studies of Orientation Tuning in the Mammalian Visual Cortex

哺乳动物视觉皮层方向调节的建模和计算研究

• 批准号: 9721430
• 负责人: Mary Pugh
• 金额: --
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-01 至 1999-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9721430&HistoricalAwards=false
• 关键词: Modeling; Computational; Studies; Orientation; Tuning

The PI, whose main area of research has been analytical and computational fluid dynamics, has recently started working with experimental neuroscientists. These neuroscientists are studying the question of orientation tuning in the mammalian visual cortex, a problem of long-standing neurobiological interest. In this collaboration, the PI has proposed mathematical models for the problem and has obtained both analytical and numerical results for the models. These results are then compared to the experimental results. Bymaking such a comparison, they find what aspects of the model produce what types of behavior. This then suggests what types of mechanisms might be present or absent at various levels of the visual cortex. The funds from this interdisciplinary grant will help the PI continue the present collaboration, start new collaborations, and broaden and deepen her background in the neurosciences. The PI will spend the year at New York University's Center for Neural Science.This IGMS project is jointly supported by the MPS Office of Multidisciplinary Activities (OMA) and the Division of Mathematical Sciences (DMS).

该 PI 的主要研究领域是分析和计算流体动力学，最近开始与实验神经科学家合作。 这些神经科学家正在研究哺乳动物视觉皮层的定向调节问题，这是一个长期以来引起神经生物学兴趣的问题。 在这次合作中，PI 提出了该问题的数学模型，并获得了模型的分析和数值结果。 然后将这些结果与实验结果进行比较。 通过进行这样的比较，他们发现模型的哪些方面产生了哪些类型的行为。 这表明视觉皮层的各个层面可能存在或不存在什么类型的机制。 这项跨学科资助的资金将帮助 PI 继续目前的合作、开始新的合作，并扩大和深化她在神经科学方面的背景。 该 PI 将在纽约大学神经科学中心度过这一年。该 IGMS 项目由 MPS 多学科活动办公室 (OMA) 和数学科学部 (DMS) 联合支持。