CAREER: Molecular Genetic Dissection of Plant Induced Resistance to Disease

9722377德莱尼基于突变筛选，SA不敏感，PI已经确定了一个基因nim1，他建议使用该基因来检测抑制子突变。这项研究的目标包括对这种抑制突变系的特征，以获得对NIM1下游反应的更多了解。另一个目标是在SAR失活的突变系中寻找新的病原体诱导基因。为此，将使用差异显示技术。最后，开发了一个突变筛选，它将识别在nim1背景中发挥作用的抗病综合征的其他成分。资助工作中包括的一个教学部分将把基因分析纳入K-12课程。

9722377 Delaney Based on a mutant screen, SA insensitivity, the PI has identified a gene, nim1, which he proposes to use for the detection of suppressor mutants. The objectives of the research include the characterization of such suppressor mutant lines, to obtain additional insight into reactions downstream of NIM1. Another objective is the search for novel pathogen-induced genes in mutant lines in which SAR is disabled. For this, differential display techniques will be used. Finally, a mutant screen is developed which will identify additional components of the disease resistance syndrome which function in the nim1 background. A teaching component included in the funded work will bring genetic analysis into the K-12 curriculum.