CAREER: Molecular Genetic Dissection of Plant Induced Resistance to Disease

职业：植物诱导抗病性的分子遗传学解析

• 批准号: 9722377
• 负责人: Terrence Delaney
• 金额: --
• 依托单位: Cornell Univ - State: AWDS MADE PRIOR MAY 2010
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2002-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9722377&HistoricalAwards=false
• 关键词: CAREER; Molecular; Genetic; Dissection; Plant

9722377 Delaney Based on a mutant screen, SA insensitivity, the PI has identified a gene, nim1, which he proposes to use for the detection of suppressor mutants. The objectives of the research include the characterization of such suppressor mutant lines, to obtain additional insight into reactions downstream of NIM1. Another objective is the search for novel pathogen-induced genes in mutant lines in which SAR is disabled. For this, differential display techniques will be used. Finally, a mutant screen is developed which will identify additional components of the disease resistance syndrome which function in the nim1 background. A teaching component included in the funded work will bring genetic analysis into the K-12 curriculum.

9722377 Delaney基于突变筛选，SA不敏感，PI已经确定了一个基因，nim1，他建议用它来检测抑制突变。该研究的目的包括表征这种抑制突变系，以获得对NIM1下游反应的进一步了解。另一个目标是在SAR失活的突变系中寻找新的病原体诱导基因。为此，将使用差分显示技术。最后，开发了一种突变筛选方法，以确定在nim1背景下起作用的抗病综合征的其他成分。资助工作中的一个教学部分将把基因分析纳入K-12课程。