Coordination and Modulation of a Reflex Motor Pattern

反射运动模式的协调和调制

• 批准号: 9723507
• 负责人: Barry Trimmer
• 金额: $ 22.49万
• 依托单位: Tufts University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9723507&HistoricalAwards=false
• 关键词: Coordination; Modulation; Reflex; Motor; Pattern

Lay Abstract PI: Trimmer, Barry A. Proposal Number: IBN-9723507 The objective of this research is to understand how reflex movements are modified and adapted for different tasks so that they are appropriate for different behaviors. Detailed analysis of movement is combined with electrical recordings from muscles both before and after different training regimes. Once the changes are described, the central nervous system mechanisms that mediate these changes are investigated by recording the electrical activity of individual nerve cells and by manipulating the chemical receptors on those nerve cells during behavioral training and during sensory stimulation. This research links adaptive changes in behavior with the cellular mechanisms underlying learning and plasticity. Its results contribute to understanding how basic rhythmic movements, such as those involved in walking, are modified as a result of experience so that the behavior can be appropriately expressed in a variety of situations and challenges.

建议编号：IBN-9723507本研究的目的是了解反射动作是如何被修改和适应于不同的任务，从而使它们适合不同的行为。对运动的详细分析结合了不同训练方案前后肌肉的电记录。一旦描述了这些变化，就可以通过记录单个神经细胞的电活动，以及在行为训练和感觉刺激期间操纵这些神经细胞上的化学受体来研究调节这些变化的中枢神经系统机制。这项研究将行为的适应性变化与学习和可塑性背后的细胞机制联系起来。它的结果有助于理解基本的有节奏的动作，如那些涉及走路的动作，是如何根据经验改变的，以便在各种情况和挑战中适当地表达行为。