1997 International Symposium: "The Ribosome-Its Nucleolar Synthesis and Structure" to be held in Noordwijkerhout, The Netherlands, August 16-20, 1997.

9725106 pickaard美国国家科学基金会为赴美参加“核糖体：其核仁合成和结构”国际研讨会的研究生和博士后提供旅费。这次会议将于1997年8月16日至20日在荷兰的北威克胡特举行。这次会议将是以前在冷泉港（1988年、1991年、1994年）举行的第四次会议。核糖体生物合成的研究包括生物化学、生物物理学、遗传学、细胞生物学、发育生物学和生理学等分支学科。许多原核生物和真核生物都是模式系统，包括大肠杆菌、酵母、棘阿米巴、锥虫、植物、果蝇和哺乳动物。核糖体合成会议汇集了来自世界各地的研究实验室，所有这些实验室都统一在一个主题下。本次会议聚集的科学家的专业知识广度促进了跨学科的互动和新见解的发展。这个会议向学生展示了他们的研究数据的更大背景，并经常向他们介绍他们第一次在不同于自己学科的复杂研究。核糖体由多个rna和大约80种蛋白质组成，它们的合成和组装必须精确协调。在真核生物中，所有三种核RNA聚合酶都需要表达必需的基因。rnas和核糖体蛋白的细胞运输也是细胞的主要后勤问题。原核生物和真核生物的控制都发生在转录起始、RNA加工、RNA转换、转录后修饰、转录终止和蛋白质转换等多个步骤中。将蛋白质和rna组装成功能性核糖体也是一个吸引结构生物学家进入该领域的问题。为了鼓励美国学生在他们的教育中寻求国际经验，会议将提供一种机制，通过这种机制，对国外博士后经历感兴趣的学生可以与实验室主任（主要在欧洲）会面，他们预计实验室将有空缺。通过这种方式，组织者希望为美国学生提供国际研究培训和经验，这与美国国家科学基金会的众多教育使命之一是一致的。核糖体在所有生物体中负责蛋白质合成。专门研究这些基本细胞“机器”的科学家将从世界各地聚集在荷兰，参加题为“核糖体：其核仁合成和结构”的会议。会议为具有广泛专业知识的科学家提供了分享该领域信息和见解的机会。美国国家科学基金会的资助将使美国研究生和博士后能够参加会议，并将为他们提供安排国际合作的机会。＊＊＊

9725106 Pikaard The National Science Foundation is providing funding for the travel of graduate students and postdoctoral fellows in the United States to attend an international symposium entitled "The Ribosome: Its Nucleolar Synthesis and Structure." This meeting will be held in Noordwijkerhout, the Netherlands, August 16-20, 1997. This conference will be the fourth incarnation of a meeting that has previously been held at Cold Spring Harbor (1988, 1991, 1994). The study of ribosome biosynthesis encompasses the sub-disciplines of biochemistry, biophysics, genetics, cell biology, developmental biology and physiology. Numerous prokaryotic and eukaryotic species are model systems including E. coli, yeast, Acanthamoeba, trypanosomes, plants, Drosophila, and mammals. Ribosome synthesis meetings bring together research laboratories from around the world, all unified by a single topic. The breadth of expertise of the scientists assembled for this meeting facilitates interdisciplinary interactions and the development of new insights. This meeting presents students with the larger context in which their research figures and often introduces them for the first time to sophisticated research in disciplines distinct from their own. Ribosomes are composed of multiple rRNAs and approximately 80 proteins whose synthesis and assembly must be precisely coordinated. In eukaryotes, all three nuclear RNA polymerases are required to express the requisite genes. Cellular trafficking of rRNAs and ribosomal proteins is also a major logistical problem for the cell. Control in both prokaryotes and eukaryotes occurs at multiple steps including transcription initiation, RNA processing, RNA turnover, post-transcriptional modification, transcription termination and protein turnover. Assembly of the proteins and rRNAs into a functional ribosome is a problem that also attracts structural biologists to this field. To encourage US students to seek out international experience in their education, the meeting will provide a mechanism by which students interested in postdoctoral experience abroad can meet with laboratory directors (mostly in Europe) who anticipate openings in their laboratories. In this way, the organizers hope to facilitate international research training and experience for American students, consistent with one of the many educational missions of the National Science Foundation. Ribosomes are responsible for protein synthesis in all organisms. Scientists specializing in the study of these essential cellular "machines" will gather from all over the world in the Netherlands for the meeting entitled "The Ribosome: Its Nucleolar Synthesis and Structure." The meeting provides scientists having a wide range of expertise the opportunity to share information and insights into this field. Funding from the National Science Foundation will enable United States graduate students and postdoctoral fellows to attend the meeting and will provide them with the opportunity to arrange international collaborations. ***