International Research Fellow Awards: Identification and Characterization of the CD4-Ligand Protein HHV-7

国际研究员奖：CD4 配体蛋白 HHV-7 的鉴定和表征

• 批准号: 9750156
• 负责人: Mark Williams
• 金额: $ 4.45万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-15 至 1999-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9750156&HistoricalAwards=false
• 关键词: International; Research; Fellow; Awards; Identification

9703804 Armitage The International Research Fellow Awards Program enables U.S. scientists and engineers to conduct three to twenty- four months of research abroad. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a three-month postdoctoral research visit by Dr. Bruce A. Armitage to work with Dr. Peter E. Nielsen at the Panum Institute in Copenhagen, Denmark. Dr. Armitage will study the interaction of peptide nucleic acid (PNA) oligomers with RNA molecules. His major hypothesis is whether the interaction of PNA with synthetic ribozyme RNA will inhibit ribozyme self-splicing. This work will give increased understanding into the interaction of PNA with folded RNA molecules, which are essential components in the development of PNA as an antisense therapeutic and diagnostic agent. Dr. Nielsen is one of the inventors of PNA and therefore is most experienced in the synthesis and application of these molecules. In addition, Nielsen's colleague, Dr. Henrik Nielsen will contribute expertise in RNA and ribozymes. Dr. Armitage completes the collaboration with his experience in quinone chemistry and photochemistry. ***

小行星9703804 国际研究员奖励计划使美国科学家和工程师能够在国外进行三到二十四个月的研究。该计划的奖项提供了联合研究的机会，以及使用国外独特或互补的设施，专业知识和实验条件。 该奖项将支持为期三个月的博士后研究访问博士布鲁斯A。阿米蒂奇将与彼得·E. 尼尔森在哥本哈根，丹麦的Panum研究所。 阿米蒂奇博士将研究肽核酸（PNA）寡聚体与RNA分子的相互作用。 他的主要假设是PNA与合成的核酶RNA的相互作用是否会抑制核酶的自我剪接。 这项工作将增加对PNA与折叠RNA分子相互作用的理解，折叠RNA分子是PNA作为反义治疗和诊断剂的发展中的重要组成部分。 Nielsen博士是PNA的发明者之一，因此在这些分子的合成和应用方面最有经验。 此外，尼尔森的同事Henrik Nielsen博士将贡献RNA和核酶方面的专业知识。 阿米蒂奇博士完成了他在醌化学和光化学的经验的合作。 ***