Enhanced NMR Capability for Organic Chemistry, Biochemistry,Molecular Biology, Physical Chemistry, Instrumental Analysisand Student Projects.

该项目的重点是通过增加几个新的附件来增强300 MHz傅里叶变换核磁共振(FT-核磁共振)系统，包括反向宽带探头、反向修改和解耦器升级、自动取样器以及补充的奔腾工作站的软件和硬件。新的反向探头和电子设备允许使用各种增敏、反向检测的核磁共振方法和其他关键实验(例如14N去耦合的1H观测)；允许在整个班级运行更多光谱(使用自动取样器)，从而极大地提高了仪器的有效利用率；并简化和扩展了与工作站的仪器使用。主要应用领域包括微型有机化学实验室、生物化学、物理化学和仪器分析。通过一些需要几个小时的高级核磁共振谱，自动取样器为大班学生单独获取光谱的问题提供了解决方案。该工作站提供更简单的处理和前台/背景技术，以提高学生获取和操作新光谱的能力。基本宏的使用使更新的1-D和2-D实验的全自动使用成为可能。这项新的调查提供了进入实验的途径，这些实验可以极大地提高本科学习的质量。

This project focuses on the enhancement of a 300 MHz Fourier-transform nuclear-magnetic resonance (FT-NMR) system with the addition of several new accessories, including an inverse broad-band probe, inverse modification and decoupler upgrade, autosampler, and software and hardware for a supplementary Pentium-based workstation. The new inverse probe and electronics are allowing access to a wide range of enhanced-sensitivity, inversely detected NMR methods and other critical experiments (such as 1H observation with 14N decoupling); enormously increasing effective use of the instrument by permitting more spectra to be run for entire classes (with the autosampler); and both simplify and extend instrument use with the workstation. Major applications will be in microscale organic chemistry laboratory, biochemistry, physical chemistry, and instrumental analysis. With some advanced NMR spectra, requiring several hours, the autosampler is providing a solution to the problem of large classes of students individually acquiring spectra. The workstation is offering simpler processing and foreground/background techniques to increase the ability of students to acquire and manipulate new spectra. Use of basic macros is making full automated use of newer 1-D and 2-D experiments possible. The new probe is providing access to experiments that provide exceptional enhancement of undergraduate studies.