Postdoctoral Research Fellowship in Biosciences Related to the Environment for FY 1998

1998财年与环境相关的生物科学博士后研究奖学金

• 批准号: 9804234
• 负责人: Zhiyong Wang
• 金额: $ 8万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-11-01 至 2000-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9804234&HistoricalAwards=false
• 关键词: Postdoctoral; Research; Fellowship; Biosciences; Related

Abstract DBI-9804234 Zhiyong Wang This action funds an NSF Postdoctoral Research Fellowship in Biosciences Related to the Environment for 1998. This fellowship provides an opportunity for the Fellow to gain additional scientific training beyond the doctoral degree and to pursue innovative and imaginative research into the fundamental mechanisms underlying the interactions between organisms and their environment at the molecular, cellular, organismal, population, community and/or ecosystem level in any area of biology supported by the Directorate for Biological Sciences of the National Science Foundation. Each fellowship supports a research and training plan to be carried out with a sponsoring scientist. The research and training plan for this fellowship is entitled genetic and molecular analysis of brassinosteroid regulation of plant development by light. Many developmental processes of plants are regulated by the environmental light conditions; and this light regulation involves the phytohormone brassinosteroids (BR). Genes mediating the BR response are being isolated as those that, when activated or mutated, can complement the developmental defects caused by insufficient synthesis of BR, such as in the det2 mutant. A putative receptor of BR (BRI1) is a membrane bound receptor kinase. Proteins that interact with or are phosphorylated by the BRI1 kinase are likely to mediate the transduction of BR signals. These proteins are being isolated using the yeast two-hybrid or phosphorylation cloning methods. Effects of light treatment on the modification and activity of BRI1 protein are being analyzed to determine how BR mediates light regulation of plant development.

DBI-9804234王志勇这一行动资助了美国国家科学基金会1998年与环境有关的生物科学博士后研究奖学金。这一奖学金为研究员提供了一个机会，使其有机会获得博士学位以外的额外科学培训，并在国家科学基金会生物科学局的支持下，在分子、细胞、有机体、种群、社区和/或生态系统层面上对任何生物领域中生物体与其环境之间相互作用的基本机制进行创新和富有想象力的研究。每个研究金支持一项研究和培训计划，该计划将与一名赞助科学家一起进行。该奖学金的研究和培训计划题为油菜素类固醇对植物发育的光调节的遗传和分子分析。植物的许多发育过程都受到环境光条件的调节，这种光调节涉及植物激素油菜素类固醇(BR)。介导BR反应的基因被分离出来，当这些基因被激活或突变时，可以补充由于BR合成不足而造成的发育缺陷，例如在Det2突变体中。BR(BRI1)受体是一种膜结合受体蛋白。与BRI1激酶相互作用或被BRI1激酶磷酸化的蛋白质可能介导BR信号的转导。这些蛋白质是用酵母双杂交或磷酸化克隆的方法分离出来的。光处理对BRI1蛋白的修饰和活性的影响正在被分析，以确定BR如何介导植物发育的光调节。