Chemical Defense in Marine Organisms

William H.斯克里普斯海洋学研究所的Fenical说， 在位于旧金山的加州大学， 迭戈，是由有机合成计划的支持，他的研究， 海洋生物的化学防御 Fenical教授探讨了 海洋植物和动物的化学生态学，以扩大我们的 了解所产生分子的来源、类型和反应性 并探索这些生物的自然功能 分子在海洋栖息地物种间的相互作用。 以下 新活性天然产物分离与结构测定 海鞘，柳珊瑚，苔藓虫和其他海洋生物， 区域选择性反应性和选择的骨架相互关系 探索次级代谢物。 该项目强调， 使用自然捕食者对纯物质进行生态相关测试， 旨在探索新类别的天然产物的化学行为 海洋生物的产品，以确定这些产品的具体作用 化合物在物种间的相互作用中发挥作用， 这些有机分子对热带雨林生物组成的影响 海洋环境。 海洋生物，包括植物和动物，产生了一系列令人震惊的 有机化合物 在有机合成计划的支持下， William H.斯克里普斯海洋学研究所的Fenical说， 在位于旧金山的加州大学， 迭戈，探索了海洋生物影响它们的化学手段， 防御 通过隔离、结构确定和测试， 各种海洋生物产生的分子。 教授 Fenical确立了用于化学反应的有机分子的性质。 防御和这些有机分子对生物的影响 热带海洋环境的组成。 另外这些 海洋化学防御的基础研究正在导致 分离具有潜在生物医学和商业价值的化合物 重要性，包括抗炎药。

Professor William H. Fenical, of the Scripps Institution of Oceanography, Geochemistry, and Marine Chemistry at the University of California at San Diego, is supported by the Organic Synthesis Program for his studies of chemical defense in marine organisms. Professor Fenical explores the chemical ecology of marine plants and animals in order to expand our knowledge of the sources, types, and reactivities of molecules produced by marine organisms and to explore the natural functions of these molecules in interspecies interactions within marine habitats. Following isolation and structure determination of new bioactive natural products from ascidians, gorgonians, bryozoans, and other marine organisms, the regioselective reactivities and skeletal interrelationships of selected secondary metabolites are explored. This project, emphasizing ecologically relevant testing of pure substances using natural predators, seeks to explore the chemical behaviors of new classes of natural products from marine organisms, to establish the specific roles these compounds play in interspecies interactions, and to define the influence of these organic molecules on the biological composition of tropical marine environments. Marine organisms, both plant and animal, produce an astounding array of organic compounds. With the support of the Organic Synthesis Program, Professor William H. Fenical, of the Scripps Institution of Oceanography, Geochemistry, and Marine Chemistry at the University of California at San Diego, explores the chemical means by which marine organisms effect their defense. Through isolation, structure determination, and testing of molecules produced by various classes of marine organisms. Professor Fenical establishes the nature of the organic molecules used for chemical defense and the influence of these organic molecules on the biological composition of tropical marine environments. In addition, these fundamental studies of marine chemical defense are resulting in the isolation of compounds of potential biomedical and commercial significance, including antiflammatory agents.