Physiology of Anopheline Mosquito Behavior

按蚊行为的生理学

• 批准号: 9807538
• 负责人: Marc Klowden
• 金额: $ 12万
• 依托单位: Regents of the University of Idaho
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2002-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9807538&HistoricalAwards=false
• 关键词: Physiology; Anopheline; Mosquito; Behavior

Klowden 9807538 In many species of mosquitoes, the females mate only once during their lives. When the males inseminate the females shortly after they emerge, they not only receive sperm to fertilize their eggs, but also products that are transferred from the accessory gland of the male. These accessory gland products have been believed to be active in the female in various ways, switching her behavior to turn off subsequent mating behavior and activate egg-laying, but these generalizations have been based on the easily colonized Aedes mosquitoes that are usually the subjects of laboratory research. None of the previous studies for which this accessory gland mechanism has been determined have examined Anopheles mosquitoes, which are important vectors of malaria. The PIs preliminary experiments indicate that in these Anopheles mosquitoes, male accessory glands indeed have no role in the behavioral switchover, although mating itself does affect the female in several ways. The PIs research will determine how Anopheles mosquitoes are affected by mating, and what possible role male accessory gland substances do play in these mosquitoes. Because future methods of mosquito control may involve the introduction of novel genes by modified males, it is important to understand the mechanisms that regulate mating in these vectors of human disease.

克洛登9807538 在许多种类的蚊子中，雌性蚊子一生中只交配一次。当雄性在雌性出现后不久使其受精时，它们不仅接受精子使其卵子受精，而且还接受从雄性附属腺转移的产物。这些附属腺产物被认为以各种方式在雌性中活跃，改变她的行为以关闭随后的交配行为并激活产卵，但这些概括是基于容易殖民的伊蚊，这些蚊子通常是实验室研究的对象。以前的研究都没有确定这种附属腺机制的研究已经检查了按蚊，这是疟疾的重要媒介。PI的初步实验表明，在这些按蚊中，雄性附腺确实在行为上没有作用，尽管交配本身确实在几个方面影响雌性。PI的研究将确定按蚊如何受到交配的影响，以及雄性附属腺物质在这些蚊子中发挥的可能作用。由于未来的蚊子控制方法可能涉及通过修饰雄性引入新基因，因此了解这些人类疾病载体中调节交配的机制非常重要。