Support for Second Metabolic Engineering Conference, October 25-30, 1998, Baveria, Germany

9812879辛斯基本次会议的目的是为代谢工程的目标和原则提供一个共识定义。第一届强调新陈代谢工程的工程基金会会议于1996年10月6日至11日在马萨诸塞州丹弗斯举行，题为“重组DNA生物技术：关注新陈代谢工程”。一个由化学工程师、计算科学家、分子生物学家和生物化学家组成的国际小组齐聚一堂，讨论代谢工程领域出现的一些重要问题。一个代表工业界、学术界和政府的国际团体出席了这次会议。组委会建议两年后在欧洲举行题为代谢工程II(ME II)的第二次会议。Me II定于1998年10月25日至30日在德国巴伐利亚州的Schlos Elmau/Oberbayern举行。ME II的一个关键目标将是试图阐明代谢工程与其他已建立的领域的主要区别，并提供这一新研究领域探索的独特视角。这里的一个重要方面是了解通过代谢途径控制通量的因素和机制。具体地说，已经规划了以下专题的会议：(1)实验和计算工具，(2)用于生产药物、燃料和化学品的代谢工程，(3)代谢工程在材料合成中的应用，(4)植物系统中的代谢工程，(5)代谢工程在蛋白质生产中的作用，(6)通过代谢工程改良菌株的进化策略，(7)医学应用和基因治疗，(8)通过调节基因进行更高水平的代谢工程，(9)代谢工程在环境问题中的应用，以及(10)未来的发展方向。***

9812879 Sinskey The objective of this conference is to provide a consensus definition of the goals and principles of Metabolic Engineering. The first Engineering Foundation conference that emphasize Metabolic Engineering was entitled "Recombinant DNA Biotechnology: Focus on Metabolic Engineering" and was held from October 6-11, 1996, in Danvers, MA. An international group of chemical engineers, computational scientists, molecular biologists and biochemists met to address a number of important issues regarding the emergence of the field of metabolic engineering. The conference was very well attended by an international group representing industry, academia and government. The organizing committee recommended that a second conference entitled Metabolic Engineering II (ME II) be held in Europe two years later. ME II is scheduled for October 25-30, 1998, at Schloss Elmau/Oberbayern (Bavaria), Germany. A key objective of ME II will be an attempt to clarify the main differences of metabolic engineering from other established fields and also to provide the unique perspectives which are explored by this new area of research. An important aspect here is understanding the factors and mechanisms contributing to the control of flux through metabolic pathways. Specifically, sessions on the following topics have been planed: (1) experimental and computational tools, (2) metabolic engineering for production of pharmaceuticals, fuels and chemicals, (3) use of metabolic engineering in the synthesis of materials, (4) metabolic engineering in plant systems, (5) role of metabolic engineering in the production of proteins, (6) evolutionary strategies for strain improvement via metabolic engineering, (7) medical applications and gene therapy, (8) higher-level metabolic engineering through regulatory genes, (9) use of metabolic engineering for environmental problems, and (10) future directions. ***