Molecular Tribology in the Biomaterials Environment

生物材料环境中的分子摩擦学

• 批准号: 9812941
• 负责人: Steve Granick
• 金额: $ 25万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2002-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9812941&HistoricalAwards=false
• 关键词: Molecular; Tribology; Biomaterials; Environment

A study will be made of the fundamental nature of boundary lubrication of biological contacts. Friction force microscopy will be used to study the boundary layer lubricant properties of biological fluids at the molecular level. It is hypothesized that chain molecules of poly (ethylene oxide), poly (ethylene glycol), and hyaluronic acid will passivate the solid surface and play the roles of additives in industrial lubricants. Surfaces passivated by these layers will be opposed to a family of reference biomaterial surfaces at well-defined, molecular-scale separations and the friction forces will be determined. Atomically smooth surfaces will also be studied. Variables will be actual surface area, normal load, adhesion, and frequency of deformation.

将对生物接触边界润滑的基本性质进行研究。摩擦力显微镜将在分子水平上研究生物流体的边界层润滑特性。假设聚环氧乙烷、聚乙二醇链分子和透明质酸分子会钝化固体表面，在工业润滑油中起到添加剂的作用。由这些层钝化的表面将在明确定义的、分子尺度的分离处与一系列参考生物材料表面相对，摩擦力将被确定。原子光滑的表面也将被研究。变量包括实际表面积、法向载荷、附着力和变形频率。