Host-Parasite Coevolution: Programme coordination an meta-analysis of Host-Parasite Coevolution

宿主-寄生虫协同进化：程序协调和宿主-寄生虫协同进化的元分析

• 批准号: 130252546
• 负责人: Professor Dr. Joachim Kurtz
• 金额: --
• 依托单位: Institut für Evolution und Biodiversität (IEB)
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2009
• 资助国家: 德国
• 起止时间: 2008-12-31 至 2013-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/130252546?language=en
• 关键词: Host; Parasite; Coevolution; Programme; coordination

The main goal of the priority programme 1399 “Host-Parasite Coevolution” is to establish host-parasite coevolution as a powerful and versatile model for analyzing the causes and processes of evolutionary adaptation. The priority programme is expected to integrate as yet isolated research efforts within Germany. The opportunity for larger, concerted research within a priority programme will enable to uncover the molecular basis of evolutionary change during host-parasite coevolution. This requires that researchers with very diverse expertise, such as evolutionary biology, parasitology and microbiology, will be included. Moreover, rather than working on just one model organism, data will be acquired from many different species of hosts and parasites. The success of such a programme thus critically relies on excellent tools for communication, data exchange and coordination within the programme and with international researchers. While primary data and specific conclusions for each study organism will be provided by the individual projects, a central meta-analysis of the expected results is required to identify general patterns and to distinguish them from species-specific ones. Based on such a meta-analysis, modelling of general patterns and processes will allow achieving a predictive framework for host-parasite coevolutionary processes. For that purpose, funding for a communication and coordination system within this priority programme and for central meta-analysis and modelling is requested.

第1399号优先方案“宿主-寄生虫共同进化”的主要目标是建立宿主-寄生虫共同进化模型，作为分析进化适应的原因和过程的一个强有力的通用模型。预计优先方案将把德国境内迄今为止孤立的研究工作结合起来。在优先方案内进行更大规模的协调一致的研究的机会将能够揭示宿主-寄生虫共同进化过程中进化变化的分子基础。这就需要包括具有各种专门知识的研究人员，如进化生物学、寄生虫学和微生物学。此外，数据将从许多不同种类的宿主和寄生虫中获得，而不是只研究一种模式生物。因此，这一方案的成功关键取决于在方案内部以及与国际研究人员进行沟通、数据交换和协调的良好工具。虽然每个项目将提供每种研究生物体的主要数据和具体结论，但需要对预期结果进行中央元分析，以确定一般模式，并将其与特定物种的模式区分开来。基于这样的元分析，一般模式和过程的建模将允许实现宿主-寄生虫共同进化过程的预测框架。为此目的，要求为这一优先方案内的通信和协调系统以及中央元分析和建模提供资金。