Enhancement of Advanced Laboratories in Molecular Biosciences and Microbiology

增强分子生物科学和微生物学先进实验室

• 批准号: 9851070
• 负责人: Barbara Taller
• 金额: $ 4万
• 依托单位: University of Memphis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9851070&HistoricalAwards=false
• 关键词: Enhancement; Advanced; Laboratories; Molecular; Biosciences

Modern, research quality instrumentation will provide the foundation for the development and implementation of new laboratory courses in biochemistry, advanced microbiology, advanced medical microbiology, and cell and developmental biology. These new courses each incorporate several separate laboratories, reducing redundancy and providing a more research-like approach by not artificially separating disciplines. The requested equipment will complement recent acquisitions to provide meaningful laboratory experiences utilizing current technologies for students planning careers as scientists or technicians. For example, Biochemistry Lab I emphasizes protein purification and characterization. As is typically done in research, students will isolate proteins by a combination of conventional chromatography, HPLC and electrophoresis. Biochemistry Lab II will emphasize recombinant DNA techniques and will use the techniques learned in Biochemistry Lab I to characterize the resulting recombinant proteins. The equipment requested will facilitate incorporation of modern techniques in HPLC, microassays, protein analysis and macrophotography into the undergraduate curriculum. Computers with Internet access will be used to design experiments, to analyze data and to prepare classroom and research presentations. Laboratory manuals will be created for each course and will be made available for distribution. The amount of equipment requested will encourage students to work in groups, promoting development of the communication, teamwork and leadership skills highly valued in many work settings.

现代化的研究质量仪器将为生物化学、高级微生物学、高级医学微生物学以及细胞和发育生物学等新实验室课程的开发和实施提供基础。这些新课程都合并了几个独立的实验室，减少了冗余，并通过不人为地划分学科，提供了一种更像研究的方法。所要求的设备将补充最近的采购，以利用当前的技术为规划科学家或技术人员职业生涯的学生提供有意义的实验室经验。例如，生物化学实验室I强调蛋白质的提纯和表征。就像研究中通常所做的那样，学生们将通过传统的层析、高效液相色谱和电泳法相结合的方法来分离蛋白质。生物化学实验II将强调重组DNA技术，并将使用在生物化学实验I中学到的技术来表征所产生的重组蛋白质。所要求的设备将促进将现代技术在高效液相色谱、微量分析、蛋白质分析和宏观摄影中纳入本科课程。可以上网的计算机将被用来设计实验、分析数据、准备课堂和研究报告。将为每门课程制作实验室手册，并将提供给分发。所需设备的数量将鼓励学生分组工作，促进在许多工作环境中高度重视的沟通、团队合作和领导技能的发展。