Computational Modeling and Measurement of Electro-Osmosis

[871994brownell]这是哺乳动物内耳外毛细胞侧壁膜电渗透作用的理论和实验研究。研究人员声称，外毛细胞可以被视为一个自然发生的微机电（MEM）系统，其中电压诱导流体通过33纳米宽的外空间输送。建立了一组微分方程来模拟系统中静电势和流体流动之间的耦合。他们将使用这个模型来预测在各种条件下施加电压对流体输送的影响。这些预测将通过外部空间内荧光分子位移的光学测量进行实验测试。目标是推导出纳米结构中电压和流体流动之间相互作用的一般原理，这些原理可用于人工MEM系统

9871994BrownellThis is theoretical and experimental research on electro-osmosis in membranes in the outer hair cell lateral wall in the mammalian inner ear. The investigators claim that the outer hair cell can be regarded as a naturally occurring microelectromechanical (MEM) system, in which voltages induce fluid transport through the 33 nm wide extracisternal space. A set of differential equations has been developed to model the coupling between electrostatic potentials and fluid flow in the system. They will use this model to predict the effects of applied voltages on fluid transport under a variety of conditions. These predictions will be tested experimentally through optical measurements of the displacement of fluorescent molecules within the extracisternal space. The goal is to derive general principles about the interaction between voltages and fluid flow in nanostructures, which can be exploited in artificial MEM systems.***