A VLSI Model of Muscular Mechanics, Architecture, and Control

[872759] deweerth这项研究的目的是探索基于生物的肌肉控制在人工系统实施中的适用性。这一目标将通过开发跨桥级肌肉模型来实现，该模型使用模拟大规模集成电路（aVLSI）实现。研究的三个具体目的是：(1)基于赫胥黎和扎哈拉克的过桥动力学公式，开发肌肉的基本功能成分肌节的aVLSI模型；(2)聚集这些模型肌节以创建肌肉纤维和肌肉单元，并评估串联/并行结构的作用和紧急功能的参数异质性；(3)将模型肌肉单元（包含激活动力学）和运动神经元结合起来形成运动单元。并创建一个由这些运动单元组成的计算机控制的肌肉控制系统。

9872759DeWeerthThe objective of this research is to explore the applicability of biologically-based muscular control to the implementation of artificial systems. This goal will be pursued through the development of a cross-bridge-level model of muscle, implemented using analog very large-scale integrated (aVLSI) circuits. The three specific aims of the research are to: (1) develop an aVLSI model of sarcomeres, the fundamental functional components of muscle, based upon the Huxley and Zahalak formulations of crossbridge dynamics, (2) aggregate these model sarcomeres to create muscle fibers and muscle units, and evaluate the role of series/paralled architecture and parameter heterogeneity of emergent functionality, and (3) combine model muscle units (incorporating activation dynamics) and motoneurons to form motor units, and create a computer controlled muscular control system consisting of an array of these motor units.