Sulfonic Acid Transformation by Anaerobic Bacteria

厌氧细菌转化磺酸

• 批准号: 9905677
• 负责人: Edward Leadbetter
• 金额: $ 31.14万
• 依托单位: University of Connecticut
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9905677&HistoricalAwards=false
• 关键词: Sulfonic; Acid; Transformation; Anaerobic; Bacteria

LeadbetterThis project's aims are to elucidate enzymological and relatedaspects of a recently recognized type of bacterial metabolism--thebiodegradation of organosulfur compounds known as sulfonic acids--thatoccurs in anoxic habitats. Such habitats are widespread on the planet.Sulfonic acids are not only biosynthetic products of a variety of animals,plants and microbes, but are products of chemical commerce (for example,household and industrial detergents, dyes, and soaps). These compoundsthus enter into both the carbon and sulfur biogeochemical cycleson the planet.It has recently been recognized that household and industrial detergentsknown as sulfonic acids can be degraded, or cycled, by bacteria thatthrive in habitats in which molecular oxygen is in limited supply. Thismetabolism of sulfonic acids results in release of sulfide, a chemicalthat has the smell of "rotten-egg" and is, in addition, corrosive to metalpipes, for example. How these particular bacteria bring about thisbiodegradation is the focus of this research project. The results of thestudy may be of value in furthering our understanding of metal deteriorationand how to minimize it, as well as to deepen our understanding ofsulfonic acids' roles in contributing to the crucial cycling of carbonand sulfur compounds on the planet.

领导该项目的目的是阐明一种最近发现的细菌代谢类型--被称为磺酸的有机硫化合物的生物降解--在缺氧生境中发生的酶学和相关方面。磺酸不仅是各种动物、植物和微生物的生物合成产物，而且是化学商业的产品(例如，家用和工业洗涤剂、染料和肥皂)。这些化合物因此进入地球上的碳和硫生物地球化学循环。最近人们认识到，被称为磺酸的家用和工业洗涤剂可以被在分子氧供应有限的生境中茁壮成长的细菌降解或循环。例如，磺酸的这种新陈代谢会导致硫化物的释放，硫化物是一种带有“臭鸡蛋”气味的化学物质，此外，它还会腐蚀金属管道。这些特殊的细菌是如何导致这种生物降解的，这是本研究项目的重点。这项研究的结果可能有助于加深我们对金属退化以及如何将其降至最低的理解，并加深我们对磺酸在促进地球上碳和硫化合物关键循环中的作用的理解。