A Unified Theoretical and Experimental Approach to Polymer Adsorption on Charged Surfaces

聚合物在带电表面吸附的统一理论和实验方法

• 批准号: 9973300
• 负责人: Stephen Webber
• 金额: $ 36万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-15 至 2003-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9973300&HistoricalAwards=false
• 关键词: Unified; Theoretical; Experimental; Approach; Polymer

9973300WebberThis project is a unified theoretical and experimental study of the adsorption of polymer micelles at surfaces. The polymer micelle exterior is made up of polyacids which can respond to changes in solution pH and/or ionic strength. It has been found that these two parameters control the density of polymer micelle attachment to an aminated surface, but the exact mechanism for this control is not understood. Experimental aspects of the project will include (1) synthesis of various block copolymers by anionic polymerization, with control of the lengths of the hydrophobic and hydrophilic blocks; (2) preparation and characterization of micelles formed by these copolymers; (3) attachment of these micelles to aminated or other modified surfaces under various pH and ionic strength conditions and characterization of the surfaces. Theoretical aspects of the project will extend the current understanding of polyelectrolyte brushes and the competition between chain distortion and energetically favorable acid-base interactions. Advances in theory will be used to help guide experiment and the results of experiment and the results of experiment will be used to test the predictions of theory.Besides the intrinsic interest in these novel structures, the project may lead to valuable advance the fields of, control of cell adhesion to surfaces, drug delivery, chemical sensing, and optical data storage.

这个项目是聚合物胶束在表面吸附的统一理论和实验研究。聚合物胶束的外部由聚酸组成，它可以对溶液pH值和/或离子强度的变化做出反应。研究发现，这两个参数控制了聚合物胶束附着在胺化表面的密度，但这种控制的确切机制尚不清楚。该项目的实验方面将包括：(1)通过阴离子聚合合成各种嵌段共聚物，控制疏水和亲水嵌段的长度；(2)这些共聚物形成胶束的制备和表征；(3)这些胶束在不同pH值和离子强度条件下与胺化或其他修饰表面的附着以及表面的表征。该项目的理论方面将扩展目前对聚电解质刷的理解，以及链畸变和能量有利的酸碱相互作用之间的竞争。理论的进步将被用来帮助指导实验，实验的结果和实验的结果将被用来检验理论的预测。除了对这些新结构的内在兴趣外，该项目还可能在细胞表面粘附控制、药物输送、化学传感和光数据存储等领域取得有价值的进展。