Postdoctoral Research Fellowship in Biological Informatics for FY 1999

1999财年生物信息学博士后研究奖学金

• 批准号: 9974193
• 负责人: Jason Wolf
• 金额: $ 10万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9974193&HistoricalAwards=false
• 关键词: Postdoctoral; Research; Fellowship; Biological; Informatics

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for 1999.The research and training plan is in the area of eukaryotic genetics and is entitled "Methods for characterizing the effect of maternal genes on the expression of early developmental traits in offspring."Genes expressed in mothers often influence the expression of traits in their offspring. These so-called maternal effects are ubiquitous but have traditionally been ignored in studies of genetic architecture (e.g., QTL analysis). Methods are being developed to incorporate maternal effects into QTL analyses and apply these methods to examine the genetics of development in the mouse.

该行动资助了1999年美国国家科学基金会生物信息学博士后研究奖学金。这项研究和培训计划是真核遗传领域的，题为“描述母体基因对后代早期发育特征表达影响的方法”。母亲体内表达的基因常常影响其后代的性状表达。这些所谓的母体效应是普遍存在的，但传统上在遗传结构研究（如QTL分析）中被忽视。目前正在开发将母体效应纳入QTL分析的方法，并应用这些方法来检查小鼠发育的遗传学。