Postdoctoral Research Fellowship in Biological Informatics for FY-1999

1999财年生物信息学博士后研究奖学金

• 批准号: 9974207
• 负责人: Dean Adams
• 金额: $ 10万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9974207&HistoricalAwards=false
• 关键词: Postdoctoral; Research; Fellowship; Biological; Informatics

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for 1999.The research and training plan is in the area of biophysics and is entitled "Comparison of three-dimensional protein structures using geometric morphometric methods: an assessment of structural similarity." Geometric morphometric algorithms are being used to identify proteins with similar three-dimensional structures. These methods compare proteins using the x,y,z coordinates of homologous points and are robust to heterogeneous variation among landmarks. They compare multiple protein structures simultaneously and can thus be used to construct a protein structure space for identifying functionally similar proteins.

这一行动资助了美国国家科学基金会1999年生物信息学博士后研究奖学金。这项研究和培训计划是在生物物理学领域，名为“使用几何形态测量学方法比较三维蛋白质结构：结构相似性的评估”。几何形态计量学算法正被用于识别具有相似三维结构的蛋白质。这些方法使用同源点的x，y，z坐标来比较蛋白质，并且对不同地标之间的异质性变化具有很强的鲁棒性。它们同时比较多个蛋白质结构，因此可以用来构建蛋白质结构空间，以识别功能相似的蛋白质。