US-Egypt Cooperative Research: Utilization of Keratin-Containing Materials by Recombinant Bacteria

美埃合作研究：重组细菌利用含角蛋白材料

• 批准号: 0001562
• 负责人: Ahmed Abdelal
• 金额: $ 2万
• 依托单位: Georgia State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0001562&HistoricalAwards=false
• 关键词: US; Egypt; Cooperative; Research; Utilization

0001562AbdelalDescription: This award is to support a collaborative project by Dr. Ahmed T. Abdelal, Professor of Biology and Dean, College of Arts and Sciences, Georgia State University, Atlanta, and Dr. Taha I. Zaghloul, Department of Biosciences and Technology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt. They plan to study the utilization of recombinant DNA technology to enhance the production of proteolytic enzymes, which are required for efficient utilization of a wide range of environmental waste materials. They also plan to develop efficient purification procedures for the proteolytic enzymes, and to characterize the purified enzymes with respect to substrate specificity and optimal conditions. The materials to be tested include keratin-containing materials such as feathers, hair, wool, and nails, which are rich in protein and carbon sources. Scope: The US Investigator, Dr. Abdelal, is recognized for his scientific and academic accomplishments and for his expertise in microbiology and in DNA research. Dr. Zaghloul, the Egyptian collaborator, has major scientific accomplishments and is well connected scientifically with researchers in the field in the USA and also in the United Kingdom where he has done preliminary investigations that will support this project. The two sides have complementary capabilities and laboratory facilities. The project will have significant value to the United States and Egypt both in increasing the scientific knowledge in this area of microbiology and in the environmental treatments of agricultural and industrial wastes. Graduate students at the University of Alexandria will participate in the research, working for short periods at Georgia State University. This proposal meets the INT objective of supporting collaborative research in areas of mutual interest. This project is being supported under the US-Egypt Joint Fund Program, which provides grants to scientists and engineers in both countries to carry out these cooperative activities.

0001562 Abdelal描述：该奖项是为了支持艾哈迈德·T.亚特兰大格鲁吉亚州立大学文理学院生物学教授兼院长阿卜杜勒·阿卜杜勒和塔哈·I博士。Zaghloul，生物科学和技术系，研究生学习和研究所，亚历山大大学，埃及亚历山大。 他们计划研究利用重组DNA技术来提高蛋白水解酶的生产，这是有效利用各种环境废料所必需的。 他们还计划为蛋白水解酶开发有效的纯化程序，并在底物特异性和最佳条件方面表征纯化的酶。 待测试的材料包括含有角蛋白的材料，如羽毛，头发，羊毛和指甲，它们富含蛋白质和碳源。适用范围：美国调查员阿卜杜勒博士因其科学和学术成就以及他在微生物学和DNA研究方面的专业知识而受到认可。 埃及合作者Zaghloul博士拥有重大的科学成就，并与美国和联合王国的研究人员在科学上有着良好的联系，他在那里进行了初步调查，将支持这一项目。双方在能力和实验室设施方面具有互补性。 该项目将对美国和埃及在增加微生物学这一领域的科学知识以及农业和工业废物的环境处理方面具有重大价值。 亚历山大大学的研究生将参加这项研究，在格鲁吉亚州立大学短期工作。 该提案符合INT的目标，即支持在共同感兴趣的领域进行合作研究。 该项目得到了美国-埃及联合基金方案的支持，该方案向两国的科学家和工程师提供赠款，以开展这些合作活动。