SenseLab: Integration of Multidisciplinary Sensory Data

该计划项目的总体目标，体现了三个研究组成部分，是利用以前的工作，由这个研究小组，涉及SenseLab，开发一套神经信息学工具，支持g嗅觉系统的功能组织的分析。 其基本原因是，在大脑功能分析中，目前实验数据的生成超过了存档、分析和整合这些数据的手段。 项目1的目的是了解嗅觉感知背后的神经操作的分子序列;为此，该项目将开发4个数据库。 项目2将进行必要的信息学研究，以支持其他两个项目，并将研究结果转移到编程核心，供实际应用。 项目3将使用开发的数据库中的数据来构建和验证嗅觉系统中相互作用的神经元的模型。 一个主要的焦点将是对僧帽细胞的嗅球的综合性能的理解。这些数据库和工具将增强对神经机制的理解。 他们将推广到其他系统，提供更广泛的使用工具，整合和搜索神经科学数据，这项研究是由国家科学基金会通过参与人脑项目，这是一个联邦机构间的研究倡议，由国会授权的一部分，“十年的大脑”的一部分。

The overall goal of this Program Project, which embodies three research components, is to capitalize on previous work by this research group, involving SenseLab, to develop a set of neuroinformatics tools for supporting g the analysis of the functional organization of the olfactory system. The underlying rational is that, in the analysis of brain function, the generation of experimental data currently exceeds the means for archiving, analyzing, and integrating these data. The aim of project 1 is to understand the molecular sequences of the neural operations underlying olfactory perception; to this end the project will develop 4 databases. Project 2 will perform the necessary informatics research to support the other two projects and transfer the results to the programming core for practical applications. Project 3 will use data in the developed databases to construct and validate models of interacting neurons in the olfactory system. A main focus will be the understanding of the integrative properties on the mitral cells for the olfactory bulb. The databases and tools will enhance the understanding of neural mechanisms. They will be generalizable to other systems, to provide tools of wider use for integrating and searching neuroscientific data.This research is funded in part by the National Science Foundation through its participation in the Human Brain Project, which is a Federal interagency research initiative, mandated by Congress as part of the "Decade of the Brain".