Interdisciplinary Grants in the Mathematical Sciences

数学科学跨学科资助

• 批准号: 0075117
• 负责人: Jerome Spanier
• 金额: $ 10万
• 依托单位: Claremont Graduate University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0075117&HistoricalAwards=false
• 关键词: Interdisciplinary; Grants; Mathematical; Sciences

This grant will provide an immersion experience for Prof. Jerome Spanier and Dr. Rong Kong at one of the premier Biomedical Optics institutions in the world, the Beckman Laser Institute and Medical Clinic (BLIMC) at the University of California at Irvine (UCI). A major thrust of the research program at BLIMC is to understand how light propagates in heterogeneous tissue. This understanding is essential to the use of the laser as an effective non-invasive diagnostic and therapeutic tool. The immersion of a small group of mathematical scientists at UCI, where there is access to an elaborate training program that prepares physical scientists for work in photomedicine, will deepen understanding of basic biological questions and provide accurate quantitative comparisons of Monte Carlo-based computer algorithms with clinical measurements. The latter is key to the development of real-time imaging techniques for non-invasive, early detection andtreatment of cancer, based on the use of laser probes.Benefits to be derived from the grant experience include: a. acceleration of the education of a cadre of mathematical scientists in the biology and medicine essential to an effective collaboration between appliedmathematicians and biomedical scientists; b. cultivation of a rich platform for additional training of mathematicians and scientists in the emerging field of tissue optics; c. enhancement of an important multidisciplinary research program aimed at real-time imaging of heterogeneous tissue using hand heldlaser probes in clinical settings; d. dissemination of new, important mathematical and computational methods for detection and treatment of disease through publications in the biomedical and applied mathematics literature and oral presentations at conferences attended by both mathematicians and biomedical scientists.This year of intense interaction will be followed by an ongoing collaboration between the two universities aimed at substantively improving their joint capability to quantify optical heterogeneities in tissues. This IGMS project is jointly supported by the MPS Office of Multidisciplinary Activities (OMA) and the Division of Mathematical Sciences (DMS).

这笔赠款将为Jerome Spiier教授和Rong Kong博士提供在世界领先的生物医学光学机构之一的加州大学欧文分校贝克曼激光研究所和医疗诊所(BLIMC)的沉浸体验。BLIMC研究计划的一个主要目的是了解光如何在不同种类的组织中传播。这种理解对于激光作为一种有效的非侵入性诊断和治疗工具的使用是至关重要的。UCI的一小群数学科学家参加了一项精心设计的培训计划，为物理科学家在光医学领域的工作做准备，这将加深对基本生物学问题的理解，并提供基于蒙特卡洛的计算机算法与临床测量的准确定量比较。后者是开发基于激光探头的非侵入性、早期发现和治疗癌症的实时成像技术的关键。赠款经验将带来的好处包括：a.加速对一批数学科学家进行生物学和医学方面的教育，这对应用数学家和生物医学科学家之间的有效合作至关重要；b.培养一个丰富的平台，用于在新兴的组织光学领域进一步培训数学家和科学家；c.加强一项重要的多学科研究方案，目的是在临床环境中使用手持激光探头对不同种类的组织进行实时成像；D.通过发表在生物医学和应用数学文献上的出版物，以及在数学家和生物医学科学家参加的会议上的口头陈述，传播用于检测和治疗疾病的新的重要的数学和计算方法。在这一年的激烈互动之后，两所大学将继续合作，旨在实质性地提高他们联合量化组织中光学异质性的能力。该IGMS项目由重大计划多学科活动办公室(OMA)和数学科学处(DMS)共同支持。