Studies of a Polyoxoanion-Derived, Record Lifetime Dioxygenase Catalyst

这个无机、生物无机和有机金属化学项目的奖项支持科罗拉多州立大学化学系的Richard Finke教授对多氧阴离子双加氧酶催化剂的研究。一个具体的重点是开发新的，更强大的和更长的寿命双加氧酶催化剂使用抗氧化多氧阴离子。该方法包括对多氧阴离子到双加氧酶催化剂演化过程的动力学和机理的研究，对真正的活性催化剂进行分离和性能的组成和结构表征，然后使用分离的催化剂将其适用性扩展到目前还不存在高效催化剂的其他反应类别。本研究的目的是开发新的催化剂，可以直接利用二氧氧化各种具有重要商业意义的芳烃、烯烃和烷烃。这些催化剂将具有重要的经济和环境影响，因为它们能够取代目前的共氧化工艺，并在芳香污染物的降解中具有潜在的应用前景。参与该项目的学生将接受分析化学、无机化学和材料化学方面的广泛培训，为他们的学术或工业生涯做好充分准备。

This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research on the development of polyoxoanion-based dioxygenase catalysts by Professor Richard Finke of the Department of Chemistry at the Colorado State University. A specific focus is the development of new, more robust and longer lifetime dioxygenase catalysts using oxidation-resistant polyoxyanions. The approach involves the performance of kinetic and mechanistic studies of the polyoxoanion-to -dioxygenase catalyst evolution process, isolation and performance of compositional and structural characterization on the true active catalyst, and then the use of the isolated catalyst to extend its applicability to additional classes of reactions for which efficient catalysts do not presently exist.The goal of this research is to develop new catalysts which can directly utilize dioxygen to oxidize a wide variety of aromatics, olefins and alkanes of commercial importance. These catalysts will have a significant economic and environmental impact due to their ability to replace current co-oxidation processes and to their potential applications in the degredation of aromatic pollutants. The students involved in this project will receive broad training in analytical, inorganic and materials chemistry and leave them well-prepared for academic or industrial careers.