Studies of a Polyoxoanion-Derived, Record Lifetime Dioxygenase Catalyst

无机，生物无机和有机化学计划的这一奖项支持科罗拉多州立大学化学系的Richard Finke教授对基于多氧阴离子的双加氧酶催化剂的开发的研究。一个具体的重点是开发新的，更强大的和更长的寿命双加氧酶催化剂使用抗氧化聚氧阴离子。该方法涉及多氧阴离子至双加氧酶催化剂演变过程的动力学和机理研究的性能，真正活性催化剂的组成和结构表征的分离和性能，然后使用分离的催化剂将其适用性扩展到目前尚不存在有效催化剂的其他类型的反应。本研究的目标是开发新的催化剂，直接利用分子氧来氧化各种具有商业重要性的芳族化合物、烯烃和烷烃。这些催化剂将有一个显着的经济和环境影响，由于它们的能力，以取代目前的共氧化过程和它们的潜在应用中的芳香族污染物的降解。参与该项目的学生将接受分析，无机和材料化学方面的广泛培训，并为他们的学术或工业生涯做好充分准备。

This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research on the development of polyoxoanion-based dioxygenase catalysts by Professor Richard Finke of the Department of Chemistry at the Colorado State University. A specific focus is the development of new, more robust and longer lifetime dioxygenase catalysts using oxidation-resistant polyoxyanions. The approach involves the performance of kinetic and mechanistic studies of the polyoxoanion-to -dioxygenase catalyst evolution process, isolation and performance of compositional and structural characterization on the true active catalyst, and then the use of the isolated catalyst to extend its applicability to additional classes of reactions for which efficient catalysts do not presently exist.The goal of this research is to develop new catalysts which can directly utilize dioxygen to oxidize a wide variety of aromatics, olefins and alkanes of commercial importance. These catalysts will have a significant economic and environmental impact due to their ability to replace current co-oxidation processes and to their potential applications in the degredation of aromatic pollutants. The students involved in this project will receive broad training in analytical, inorganic and materials chemistry and leave them well-prepared for academic or industrial careers.