Molecular Isotopic Tools for Environmental Research (MITER)

这个环境分子科学合作研究活动（CRAEMS）奖给伍兹霍尔海洋研究所是由化学部特别项目办公室支持的。 该奖项支持研究所的Timothy埃格林顿，John Hayes和Christopher Reddy的研究，以确定特定污染物（如碳氢化合物和氯化有机物）携带的天然和引入的同位素标记，并追踪它们进入大分子环境有机基质的通道，如腐殖酸和富里酸物质。 此外，他们还研究了有机结合污染物的生物利用度，并确定了这些化合物与其游离、未结合的对应物相比的长期命运。碳-14测量，与13 C-，2 H-和15 N-标记技术，用于检测污染物及其代谢物在受影响的沉积物和土壤，并遵循碳进入生物池。在实验室培养和污染场地的实地研究中，通过核磁共振和质谱技术追踪同位素标记。除了为分子水平的过程提供新的见解外，这项工作还旨在开发新的分子同位素工具来研究环境问题。还通过一个分奖为俄亥俄州州立大学的迈克尔·弗雷塔斯提供支持。了解控制污染物结合和释放到环境中的机制对人类健康至关重要。这些研究旨在从数量上了解在复杂的环境基质中隔离的一系列半挥发性污染物的命运。

This Collaborative Research Activities in Environmental Molecular Science (CRAEMS) Award to Woods Hole Oceanographic Institution is supported by the Special Projects Office in the Chemistry Division. This award supports the studies Timothy Eglinton, John Hayes, and Christopher Reddy at the Institute to determine natural and introduced isotopic labels carried by specific contaminants such as hydrocarbons and chlorinated organics, and to trace their passage into macromolecular environmental organic matrices, such as humic and fulvic substances. In addition, they examine the bioavailability of organically bound contaminants and determine the long-term fate of these compounds compared with their free, unbound counterparts. Carbon-14 measurements, in tandem with 13C-, 2H-, and 15N- labeling techniques, are used to detect pollutants and their metabolites in impacted sediments and soils and to follow the carbon into biological pools. Isotopic labels are tracked by both NMR and mass spectrometric techniques in both laboratory incubation and field studies of contaminated sites. In addition to providing new insights into molecular-level processes, this work aims to develop new molecular-isotopic tools to study environmental problems. Support is also provided for Michael Freitas at Ohio State University through a subaward.Understanding the mechanisms that control binding and release of contaminants into the environment is of critical importance to human health. These studies are designed to develop a quantitative understanding of the fate of a range of semi-volatile pollutants sequestered in complex environmental matrices.