Molecular Isotopic Tools for Environmental Research (MITER)

环境研究分子同位素工具 (MITRE)

基本信息

  • 批准号:
    0089172
  • 负责人:
  • 金额:
    $ 299万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2000
  • 资助国家:
    美国
  • 起止时间:
    2000-09-15 至 2005-08-31
  • 项目状态:
    已结题

项目摘要

This Collaborative Research Activities in Environmental Molecular Science (CRAEMS) Award to Woods Hole Oceanographic Institution is supported by the Special Projects Office in the Chemistry Division. This award supports the studies Timothy Eglinton, John Hayes, and Christopher Reddy at the Institute to determine natural and introduced isotopic labels carried by specific contaminants such as hydrocarbons and chlorinated organics, and to trace their passage into macromolecular environmental organic matrices, such as humic and fulvic substances. In addition, they examine the bioavailability of organically bound contaminants and determine the long-term fate of these compounds compared with their free, unbound counterparts. Carbon-14 measurements, in tandem with 13C-, 2H-, and 15N- labeling techniques, are used to detect pollutants and their metabolites in impacted sediments and soils and to follow the carbon into biological pools. Isotopic labels are tracked by both NMR and mass spectrometric techniques in both laboratory incubation and field studies of contaminated sites. In addition to providing new insights into molecular-level processes, this work aims to develop new molecular-isotopic tools to study environmental problems. Support is also provided for Michael Freitas at Ohio State University through a subaward.Understanding the mechanisms that control binding and release of contaminants into the environment is of critical importance to human health. These studies are designed to develop a quantitative understanding of the fate of a range of semi-volatile pollutants sequestered in complex environmental matrices.
这个环境分子科学合作研究活动(CRAEMS)奖给伍兹霍尔海洋研究所是由化学部特别项目办公室支持的。 该奖项支持研究所的Timothy埃格林顿,John Hayes和Christopher Reddy的研究,以确定特定污染物(如碳氢化合物和氯化有机物)携带的天然和引入的同位素标记,并追踪它们进入大分子环境有机基质的通道,如腐殖酸和富里酸物质。 此外,他们还研究了有机结合污染物的生物利用度,并确定了这些化合物与其游离、未结合的对应物相比的长期命运。碳-14测量,与13 C-,2 H-和15 N-标记技术,用于检测污染物及其代谢物在受影响的沉积物和土壤,并遵循碳进入生物池。在实验室培养和污染场地的实地研究中,通过核磁共振和质谱技术追踪同位素标记。除了为分子水平的过程提供新的见解外,这项工作还旨在开发新的分子同位素工具来研究环境问题。还通过一个分奖为俄亥俄州州立大学的迈克尔·弗雷塔斯提供支持。了解控制污染物结合和释放到环境中的机制对人类健康至关重要。这些研究旨在从数量上了解在复杂的环境基质中隔离的一系列半挥发性污染物的命运。

项目成果

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专利数量(0)

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Timothy Eglinton其他文献

Deglacial Ventilation History in the North Pacific Mid-DeepWater:Implications for Active North Pacific Deep Water Formation Synchronized with Atlantic Meridional Overtuming Circulation
北太平洋中深水冰消风历史:与大西洋经向翻转环流同步的活跃北太平洋深水层的意义
  • DOI:
  • 发表时间:
    2008
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Masao Uchida;Kenichi Ohkushi;James P. Kennett;Timothy Eglinton;Katsunori Kimoto;and Yasuyuki Shibata
  • 通讯作者:
    and Yasuyuki Shibata
Vascular pedicle dissection time in laparoscopic colectomies as a novel marker of surgical skill: a prospective cohort study
  • DOI:
    10.1007/s10151-025-03121-7
  • 发表时间:
    2025-03-22
  • 期刊:
  • 影响因子:
    2.900
  • 作者:
    Kirsten de Burlet;Isaac Tranter-Entwistle;Jeffrey Tan;Anthony Lin;Siraj Rajaratnam;Saxon Connor;Timothy Eglinton
  • 通讯作者:
    Timothy Eglinton
Functional links between the microbiome and the molecular pathways of colorectal carcinogenesis
  • DOI:
    10.1007/s10555-024-10215-5
  • 发表时间:
    2024-09-28
  • 期刊:
  • 影响因子:
    8.700
  • 作者:
    Jessica Permain;Barry Hock;Timothy Eglinton;Rachel Purcell
  • 通讯作者:
    Rachel Purcell

Timothy Eglinton的其他文献

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{{ truncateString('Timothy Eglinton', 18)}}的其他基金

Enhancement of Capabilities for Molecular-Level Radiocarbon Studies of Water Column and Sedimentary Organic Matter
增强水体和沉积有机质的分子水平放射性碳研究能力
  • 批准号:
    0648347
  • 财政年份:
    2007
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Influence of Pre- and Post-depositional Processes on Sedimentary Organic Matter Composition
沉积前后过程对沉积有机质组成的影响
  • 批准号:
    0526268
  • 财政年份:
    2005
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Collaborative Research: Changing Holocene Environments of the Eastern Tropical Atlantic (CHEETA)
合作研究:改变热带大西洋东部的全新世环境(CHEETA)
  • 批准号:
    0402533
  • 财政年份:
    2004
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Advective Controls on Organic Carbon Export and Burial on the Northwest Atlantic Margin
对西北大西洋边缘有机碳输出和埋藏的平流控制
  • 批准号:
    0425677
  • 财政年份:
    2004
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
The Influence of Sediment Dynamics on Molecular and Microfossil Proxy Records
沉积物动力学对分子和微化石代理记录的影响
  • 批准号:
    0327405
  • 财政年份:
    2003
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Temporal Constraints on the Delivery of Terrestrial Organic Carbon to Marine Sediments
陆地有机碳向海洋沉积物输送的时间限制
  • 批准号:
    0137005
  • 财政年份:
    2002
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Acquisition of a Gas Chromatography/Time of Flight-Mass Spectrometry (GC/TOF-MS) System for Ultra-High Resolution Molecular Stratigraphy
获取用于超高分辨率分子地层学的气相色谱/飞行时间质谱 (GC/TOF-MS) 系统
  • 批准号:
    0094475
  • 财政年份:
    2001
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
COLLABORATIVE RESEARCH: Carbon-Limitation in Pleistocene Tropical Ecosystems: A Test of the Roles of CO2 and Aridity Using Molecular and Isotopic Proxies
合作研究:更新世热带生态系统中的碳限制:使用分子和同位素代理测试二氧化碳和干旱的作用
  • 批准号:
    9903473
  • 财政年份:
    1999
  • 资助金额:
    $ 299万
  • 项目类别:
    Continuing Grant
Constraints on Organic Carbon Inputs to Continental Margin Sediments: A Coupled Molecular Isotopic Approach
大陆边缘沉积物有机碳输入的限制:耦合分子同位素方法
  • 批准号:
    9907129
  • 财政年份:
    1999
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant
Workshop on Alkenone-Based Paleoceanographic Indicators
基于烯酮的古海洋学指标研讨会
  • 批准号:
    9902683
  • 财政年份:
    1999
  • 资助金额:
    $ 299万
  • 项目类别:
    Standard Grant

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Tracing element pathways and processes of Ca, Fe, Cu, and Zn in the geosphere and biosphere: Precision measurement with isotopic tools
追踪地质圈和生物圈中 Ca、Fe、Cu 和 Zn 的元素路径和过程:使用同位素工具进行精确测量
  • 批准号:
    RGPIN-2020-04212
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使用社区生态系统模型和同位素工具了解英国水域缺氧的控制
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