Microbial Ecology and Genomics: Understanding the Patterns and Processes of Single Cells, Communities and the Ecosphere; February 23-25, 2001 in Southern California

现已知，培养中的微生物物种不能很好地代表它们的自然多样性--这使为可见世界确立的惯例相形见绌。这是在过去十年中使用较新的分子工具来探索环境多样性而揭示出来的，并引发了微生物生态和技术的爆炸性增长，这些技术可能会受益于丰富的自然生化多样性。几次座谈会和会议帮助制定了政策建议，使这些领域的研究计划得以持续。拟议中的研讨会的主要目标是提供一个论坛，以应对最近明显的科学机会和研究挑战。我们将如何将基因组序列信息带回环境？环境是基因组进化、运作和继续进化的环境。这是唯一可以完全理解它们的背景。我们建议我们明确评估微生物系统学可能发挥的新作用。微生物系统学将在为目前正在产生的海量基因组信息提供秩序方面发挥什么作用？基因组信息是如何在环境中打包的？基因组序列与表型之间有什么关系？关于进化和适应性辐射的基本机制，比较基因组学告诉了我们什么？在我们能够在这一领域取得进展之前，必须解决这些问题。

0090711ColganIt is now known that microbial species in culture poorly represent their natural diversity-which dwarfs conventions established for the visible world. This was revealed over the last decade using newer molecular tools to explore environmental diversity and has sparked an explosive growth in microbial ecology and technologies that may profit from the bounty of natural biochemical diversity. Several colloquia and meetings have helped formulate policy recommendations to enable sustained research programs in these areas.The primary objective of the proposed workshop is to provide a forum to address science opportunities and research challenges recently made evident. How will we take genome sequence information back to the environment? The environment is the context in which genomes evolved, function, and continue to evolve. It is the only context in which they can be fully understood. We suggest that we explicitly evaluate possible new roles of microbial systematics. What role will microbial systematics play in providing order to the immense amount of genomic information now being generated? How is genomic information packaged in the environment? What is the relationship between genome sequence and phenotype? What is comparative genomics telling us about the basic mechanisms of evolution and adaptive radiation? These questions must be addressed before we can move forward in this field.