U.S.- Italy Cooperative Research: ESR Investigation of Interactions of Nanoparticles of Dendrimers/Liposomes with Polymers and Surfactants

美国-意大利合作研究：树枝状聚合物/脂质体纳米粒子与聚合物和表面活性剂相互作用的ESR研究

• 批准号: 0091547
• 负责人: Ponisseril Somasundaran
• 金额: $ 4万
• 依托单位: Columbia University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-15 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0091547&HistoricalAwards=false
• 关键词: U.S.; Italy; Cooperative; Research; ESR

0091547SomasundaranThis two-year award, which supports U.S.-Italy cooperative research on interactions of nanoparticles of dendrimers/liposomes with polymers and surfactants, involves Ponisseril Somasundaran of Columbia University and M.F. Ottaviani of the Institute of Chemical Sciences in Urbino, Italy. The objective of their research is to enable the use of electron spin resonance to monitor conformation of polymers and surfactants at interfaces. The U. S. principal investigator brings to this collaboration his group's expertise in identifying the best conformation of polymers and proteins for determining the interactions between nanoparticles and dendrimers with surface active species. The US co-PI provides experience with applied supramolecular structure-function and structure-reactivity relationships toward understanding the behavior of adsorption at interfaces. This work is complemented by the Italian investigator's expertise in the use of electron spin resonance probes for examination of adsorption at interfaces. The results of this research are expected to contribute to knowledge of the behavior of vital industrial systems.

0091547 Somasundaran该奖项为期两年，支持美国和意大利在树枝状大分子/脂质体纳米颗粒与聚合物和表面活性剂相互作用方面的合作研究，获奖者包括哥伦比亚大学的Ponisseril Somasundaran和意大利乌尔比诺化学科学研究所的M.F.Ottaviani。他们的研究目标是能够使用电子自旋共振来监测聚合物和表面活性剂在界面上的构象。这位美国首席研究员将他的团队在确定聚合物和蛋白质的最佳构象方面的专业知识带到了这次合作中，以确定纳米颗粒和树枝状大分子与表面活性物种之间的相互作用。美国的co-PI提供了应用超分子结构-功能和结构-反应性关系的经验，以了解界面上的吸附行为。这项工作得到了意大利研究人员在使用电子自旋共振探头检查界面吸附方面的专业知识的补充。这项研究的结果预计将有助于了解重要工业系统的行为。