Postdoctoral Research Fellowship in Microbial Biology for FY2001

这一行动为2001财政年度NSF微生物生物学博士后奖学金提供资金。 该研究金支持关于原生动物、微藻、真菌、古菌、细菌和病毒物种的基础生物学的培训和研究，这些物种通常不被视为模式生物。此外，它为最近的博士生提供了机会，以获得微生物生物学方面的额外培训，在既定科学家的赞助下获得研究经验，并拓宽他/她的科学视野，超越本科和研究生培训期间的研究经验。这些奖学金还旨在帮助新科学家指导他们的研究工作，跨越传统学科，并利用独特的研究资源，地点和设施，包括外国地点。研究和培训计划的标题是“利用生物化学和遗传学方法来剖析蓝藻如何感知和应对不断变化的光照条件。“试验微生物是双倍管弗氏菌。 RcaE是一种假定的光敏色素样感光细胞，控制着互补色适应（CCA）的过程，目前正在进行详细的生化分析。具体而言，实验解决了磷酸化模型，该模型认为RcaE是在不同光质量下差异控制响应调节剂RcaF的磷酸化状态的光感受器，这反过来又调节RcaC的磷酸化水平。

This action funds an NSF Postdoctoral Fellowship in Microbial Biology for FY2001. The fellowship supports training and research on the basic biology of protozoan, microalgal, fungal, archaeal, bacterial and viral species that are not generally considered to be model organisms. Further, it provides opportunities for a recent doctoral recipients to obtain additional training in microbial biology, to gain research experience under the sponsorship of established scientists, and to broaden his/her scientific horizons beyond the research experiences during the undergraduate and graduate training. These fellowships are further designed to assist new scientists to direct their research efforts across traditional disciplinary lines and to avail themselves of unique research resources, sites, and facilities, including foreign locations. The research and training plan is entitled "Utilizing biochemical and genetic methods to dissect how a cyanobacterium senses and responds to changing light conditions." The test organism is Fremyella diplosiphon. A detailed biochemical analysis is being made of RcaE, a putative phytochrome-like photoreceptor that controls the process of complementary chromatic adaptation (CCA). Specifically, the experiments address the phosphorelay model which holds that RcaE is the photoreceptor that differentially controls the phosphorylation state of the response regulator RcaF in different light qualities, which in turn regulates the phosphorylation levels of RcaC.