Nano Initiative: The Single-Molecule DNA Transistor

纳米计划：单分子 DNA 晶体管

• 批准号: 0103215
• 负责人: Lydia Sohn
• 金额: $ 10万
• 依托单位: Princeton University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-15 至 2003-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0103215&HistoricalAwards=false
• 关键词: Nano; Initiative; Single; Molecule; DNA

EIA-0103215Lydia SohnPrinceton UniversityNano Exploratory Research: The Single-Molecule DNA TransferThe focus of this project is to investigate the possibility of using single molecules of DNA for molecular-based electronic devices. Recent results of single-molecule DNA transistor shows a Coulomb Blockade Staircase and a gate-voltage dependence of the conductance enabling reliable and reproducible conducting DNA devices. This project is furthering this work to investigate the mechanism for DNA conduction and its dependence on various chemical and structural parameters. The single-molecule DNA transistor is being further investigated too understand the mechanism by which DNA conducts. Various questions such as dependence of conductivity of DNA to length and sequence; differences in conductivity between single-stranded and doubled-stranded DNA; dependence of the conduction in DNS to salts from the buffer solution; where are possible scattering centers located in the DNA molecule? Answers to such fundamental questions are expected to lead to a number of future novel molecular-scaled DNA-based electronic devices.

lydia soh普林斯顿大学纳米探索性研究：单分子DNA转移这个项目的重点是研究将单分子DNA用于分子电子设备的可能性。单分子DNA晶体管的最新研究结果显示，库仑封锁阶梯和电导的栅极电压依赖性使得可靠和可复制的导电DNA器件成为可能。本项目正在进一步研究DNA传导的机制及其对各种化学和结构参数的依赖。单分子DNA晶体管正在进一步研究，以了解DNA导电的机制。各种各样的问题，如DNA的导电性对长度和序列的依赖性；单链和双链DNA的传导性差异；DNS电导率对缓冲溶液中盐的依赖性；DNA分子中可能的散射中心在哪里？这些基本问题的答案有望导致未来一些新颖的分子尺度dna电子设备。